概述| 货号 | RDC0533 |
| 别名 | HHF7; malignant T cell amplified sequence 1; Malignant T-Cell-Amplified Sequence 1; MCT-1; Multiple Copies T-Cell Malignancies; SLC16A1 |
全称 | Monocarboxylic Acid Transporter 1 (Solute Carrier Family 16 Member 1) | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6566 (Human); 20501 (Mouse); 25027 (Rat) |
| 背景 | MCT1/SLC16A1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. SLC16A1 may be a potential therapeutic target combining antimetabolic and anti-angiogenic activities. SLC16A1 blockers could act as HIF-1 inhibitors leading to anti-angiogenic effects. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Blood-brain Barrier Transporters
- Glucose Homeostasis
- Solute Carrier Family (SLC)
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