概述货号 | RDC0486 |
别名 | ATP receptor; MGC20089; P2RX7; P2X purinoceptor 7; P2X7P2X7 receptor; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7 variant A; Purinergic receptor |
全称 | P2X Purinergic Receptor 7 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 5027 (Human); 18439 (Mouse); 29665 (Rat) |
背景 | P2RX7 belongs to the family of purinoceptors for ATP. It functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. P2RX7 antagonists have emerged as novel therapeutics for the treatment of acute inflammation, pain and fever, with wider anti-inflammatory activity than currently used cyclooxygenase inhibitors. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | |