概述货号 | RDC0430 |
别名 | Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; Ileal Na(+)/bile acid cotransporter; ileal sodium/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; ISBT; Na(+)-dependent ileal bile acid transporter; NTCP2; NTCP2PBAM; PBAM; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; Solute carrier family 10 member 2 |
全称 | Solute Carrier Family 10 (Sodium/Bile Acid Cotransporter Family) Member 2 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 6555 (Human); 20494 (Mouse); 29500 (Rat) |
背景 | SLC10A2 is a sodium/bile acid cotransporter that is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so SLC10A2 is also critical for cholesterol homeostasis. Mutations in SLC10A2 cause primary bile acid malabsorption and may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Lipid & Fatty Acid Transport
- Solute Carrier Family (SLC)
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