概述| 货号 | RDC0365 |
| 别名 | anterior pharynx defective 1 homolog B (C. elegans); PSFL |
全称 | Anterior Pharynx Defective 1 Homolog B | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 83464 (Human); 208117 (Mouse); 300802 (Rat) |
| 背景 | APH1B encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. APH1B represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - APP Cleavage and Amyloid-beta Degradation
- Aspartic Proteases and Regulators
- Cell to Cell Adhesion Disassembly During EMT
- Notch Family
- Notch Pathway
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