概述货号 | RDC0353 |
别名 | gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; MGC126722; PGQTL2 |
全称 | Gastric Inhibitory Polypeptide Receptor | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 2696 (Human); 381853 (Mouse); 25024 (Rat) |
背景 | GIPR is a G protein-coupled receptor for gastric inhibitory polypeptide (GIP). GIP was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking GIPR exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defects in this gene may contribute to the pathogenesis of diabetes. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Diabetes
- Glucose Homeostasis
- Neurotransmitter G Protein-Coupled Receptors
- Peptide Hormone G Protein-Coupled Receptors
- Protein/Peptide Hormones and Regulators
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