Human PTGDR VersaClone cDNA (10 UG)
货号：
RDC0240 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0240 |
| 别名 | AS1; ASRT1; DP; DP1; MGC49004; PGD receptor; PGD2 receptor; prostaglandin D2 receptor (DP); prostaglandin D2 receptor; Prostanoid DP receptor; PTGDR1 |
全称 | Prostaglandin D2 Receptor | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5729 (Human); 19214 (Mouse); 498475 (Rat) |
| 背景 | PTGDR is a G protein-coupled receptor that has been shown to function as a prostanoid DP receptor. PTGDR is expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of PTGDR, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Genetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Bioactive Lipid G Protein-Coupled Receptors
- Eicosanoids and Regulators
- Prostanoids and Receptors
- Steroid Hormones and Bioactive Lipids
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