概述| 货号 | RDC0219 |
| 别名 | EBI2Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupledreceptor); EBV-induced G-protein coupled receptor 2; Epstein-Barr virus-induced G-protein coupled receptor 2; G protein-coupled receptor 183; GPR183; G-protein coupled receptor 183 |
全称 | Epstein-Barr Virus Induced Gene 2 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1880 (Human); 321019 (Mouse); 679975 (Rat) |
| 背景 | EBI2 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. EBI2 is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor and signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. EBI2 is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. EBI2 is an orphan receptor that plays a central role during humoral immunity and promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
