Rat CCR3 (NP 446410) VersaClone cDNA (10 UG)
货号：
RDC0328 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0328 |
| 别名 | b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; CCR3; CCR-3; CD193 antigen; CD193; chemokine (C-C motif) receptor 3; CKR3CC-CKR-3CMKBR3CD193; eosinophil CC chemokine receptor 3; Eosinophil eotaxin receptor; MGC102841 |
| 反应种属 | Rat |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine) |
| 背景 | CCR3 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR3 is 355 amino acids (aa) in length with a predicted molecular weight of 41 kDa. Mouse and rat CCR3 share 70% and 68% aa sequence identity with the human protein, respectively. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Airway Inflammation and Remodeling
- Basophils
- CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Eosinophils
- Human CD Marker Products
- Myeloid Lineage Markers
- T Cell Migration/Adhesion
- Th2 Cells
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