Rat CXCR5 (NP 445755) VersaClone cDNA (10 UG)
货号：
RDC0037 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0037 |
| 别名 | BLR1; BLR1MDR-15; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CD185 antigen; CD185; chemokine (C-X-C motif) receptor 5; C-X-C chemokine receptor type 5; CXCR5; CXC-R5; MDR15CXCR-5; MGC117347; Monocyte-derived receptor 15 |
| 反应种属 | Rat |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 643 (Human); 12145 (Mouse); 29363 (Rat) |
| 背景 | CXCR5, also known as Burkitt Lymphoma Receptor 1, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR5 is 372 amino acids (aa) in length with a predicted molecular weight of 42 kDa. Mouse and rat CXCR5 share 83% and 81% aa sequence identity with the human protein, respectively. CXCR5 is primarily expressed on B cells and binds CXCL13/BCL/BCA-1. The CXCL13/BCL/BCA-1:CXCR5 axis regulates B cell migration within secondary lymphoid organs such as the spleen and Peyer’s patches. CXCR5 is also expressed on follicular helper T cells and dermal-derived migratory dendritic cells where it is thought to promote the humeral immune response by meditating germinal center reactions and B cell activation. Polymorphisms of CXCR5 are associated with multiple types of non-Hodgkin’s lymphoma, and it is expressed on Burkitt’s lymphoma cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Chemotaxis, Migration, and Adhesion
- B Cell Markers
- Chemokine Receptors
- Chemokines and Receptors in Angiogenesis
- Chemokines and Receptors in Tfh Cell Differentiation and Function
- Human CD Marker Products
- ICC / IHC Images: CXCR5
- LTi Cells
- T Cell Migration/Adhesion
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