Rat CCR2 (NP 068638) VersaClone cDNA (10 UG)
货号：
RDC0327 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0327 |
| 别名 | C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor |
| 反应种属 | Rat |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 729230 (Human); 12772 (Mouse); 60463 (Rat) |
| 背景 | CCR2 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR2 is 374 amino acids (aa) in length with a predicted molecular weight of 42 kDa. Mouse and rat CCR2 share 80% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Human CD Marker Products
- Macrophage Activation Markers
- Monocyte Markers
- Myeloid Lineage Markers
- Myeloid-derived Suppressor Cells (MDSC)
- Neuroinflammation
- Proinflammatory Cytokines & CCR2 Promote Estrogen-deficient Bone Loss
- Receptors in the Jak/STAT Pathway
- Regulatory T Cells (Tregs)
- T Cell Migration/Adhesion
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