Rat CXCR1/IL-8 RA (NP 062183) VersaClone cDNA (10 UG)
货号：
RDC0241 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0241 |
| 别名 | CD128; CD181 antigen; CD181; CDw128aC-C; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor type 1; IL-8R A; IL8R1; IL8RA; IL8RAC-C-CKR-1; IL8RBA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A |
全称 | Interleukin 8 Receptor A | | 反应种属 | Rat |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3577 (Human); 227288 (Mouse); 54258 (Rat) |
| 背景 | CXCR1, also known as IL-8 RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8 RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cancer Stem Cell Markers
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- CXC Chemokines and Receptors
- Dendritic Cells: A New Immunotherapy?
- Human CD Marker Products
- Macrophage Activation Markers
- Megakaryocytes
- Mini-review: Multiple Sclerosis: Immune Cell Access to the Central Nervous System
- Monocyte Markers
- Neuroinflammation
- Neutrophils
- T Cell Migration/Adhesion
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