概述货号 | RDC1699 |
别名 | FLJ27515; Smuckler; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell membrane protein 4; TIM4; TIM-4; TIMD4; TIMD-4 |
全称 | T Cell Immunoglobulin Mucin-4 | 反应种属 | Cynomolgus Monkey |
性能供应商 | R&D Systems |
Entrez Gene IDs | 91937 (Human); 276891 (Mouse); 102140672 (Cynomolgus Monkey) |
背景 | TIM-4 is a type I membrane protein belonging to the TIM family of cell surface receptors that regulate Th1 and Th2 cell responses. The extracellular region of TIM-4 has an RGD containing V-type Ig-like domain and a serine/threonine-rich mucin domain. Unlike other TIM family members, its intracellular tail lacks tyrosine-phosphorylation motifs. TIM-4 is a ligand for TIM-1, which is also known as hepatitis A virus cellular receptor (HAVCR). The extracellular domain of human TIM-4 shares 53% amino acid sequence identity with that of mouse TIM-4. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Co-stimulatory and Co-inhibitory Molecules
- Infectious Diseases
- Mouse Tissue-Resident Macrophage Markers
- Special Glycoproteins
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