产品中心
当前位置：首页>产品中心Anti-PAIP2
货号： bs-21007R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-21007R
- 英文名称
- PAIP2
- 中文名称
- 多聚腺苷酸结合蛋白相互作用蛋白2抗体
- 别 名
- PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 15kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PAIP2:51-127/127
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
PAIP2 (Poly(A) Binding Protein Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Translational Control and TGF-Beta Pathway. GO annotations related to this gene include mRNA binding and translation repressor activity. An important paralog of this gene is PAIP2B.
Function:
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Subunit:
Interacts with the RRM1-RRM2 and C-terminus regions of PABPC1 in a 1:1 stoichiometry. Interacts with EIF4A.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the PAIP2 family.
SWISS:
Q9BPZ3
Gene ID:
51247
Database links:Entrez Gene: 416187Chicken
Entrez Gene: 536619Cow
Entrez Gene: 51247Human
Entrez Gene: 67869Mouse
Entrez Gene: 361309Rat
Omim: 605604Human
SwissProt: Q5ZJS6Chicken
SwissProt: Q3ZC67Cow
SwissProt: Q9BPZ3Human
SwissProt: Q9D6V8Mouse
SwissProt: Q6AXZ0Rat
Unigene: 396644Human
Unigene: 126534Mouse
Unigene: 1073Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.