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货号： bs-21006R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-21006R
- 英文名称
- PAIP1
- 中文名称
- 多聚腺苷酸结合蛋白相互作用蛋白1抗体
- 别 名
- MGC12360; OTTHUMP00000221601; OTTMUSP00000026880; PABC1 interacting protein 1; PABP interacting protein 1; PABP-interacting protein 1; PAIP 1; PAIP-1; Paip1; PAIP1_HUMAN; Poly(A) binding protein interacting protein 1; Poly(A)-binding protein-interacting protein 1; Polyadenylate binding protein interacting protein 1; Polyadenylate-binding protein-interacting protein 1.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 54kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PAIP1:51-150/479
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Function:
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Subcellular Location:
Cytoplasm.
Similarity:
Contains 1 MIF4G domain.
SWISS:
Q9H074
Gene ID:
10605
Database links:Entrez Gene: 510246Cow
Entrez Gene: 10605Human
Entrez Gene: 218693Mouse
Entrez Gene: 365684Rat
Omim: 605184Human
SwissProt: Q9H074Human
SwissProt: Q8VE62Mouse
Unigene: 482038Human
Unigene: 132584Mouse
Unigene: 9450Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.