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货号： bs-19991R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19991R
- 英文名称
- PPP1R1C
- 中文名称
- 蛋白磷酸酶1调节亚基1c抗体
- 别 名
- Inhibitor 5 of protein phosphatase 1; IPP5; PP1 inhibitor protein 5; Ppp1r1c; PPR1C_HUMAN; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1, regulatory (inhibitor) subunit 1C.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 12kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PPP1R1C:1-100/567
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Function:
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).
Post-translational modifications:
Phosphorylation at Ser-56 favors interaction with CALM1.
Isoform 1 is methylated by CARM1 in immature thymocytes.
Similarity:
Contains 1 R3H domain.
SWISS:
Q8WVI7
Gene ID:
151242
Database links:Entrez Gene: 10777Human
Entrez Gene: 74100Mouse
Entrez Gene: 363153Rat
Omim: 605488Human
SwissProt: Q9UBL0Human
SwissProt: Q9DCB4Mouse
Unigene: 475902Human
Unigene: 713605Human
Unigene: 297444Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.