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货号： bs-19980R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19980R
- 英文名称
- PRA1/PRAF1
- 中文名称
- PRA1蛋白抗体
- 别 名
- PRA1 domain family 1; PRA1 family protein 1; PRAF1; PRAF1_HUMAN; prenylated Rab acceptor 1; Prenylated Rab acceptor protein 1; Rab acceptor 1 (prenylated); RABAC1; YIP3.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PRA1:1-100/185 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- Function:
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
Subunit:
Homodimer. Interacts with VAMP2 (synaptobrevin-2), GDI1,and PCLO (By similarity). Interacts specifically with prenylated Rab proteins; strongly with RAB4B, RAB5A and RAB5C, and weakly with RAB4A, RAB6, RAB7A, RAB17 and RAB22. Interacts with NDRG1.
Subcellular Location:
Cell membrane. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle. According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Tissue Specificity:
Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach.
DISEASE:
In fetal tissues, it is more abundant in kidney and lung.
Similarity:
Belongs to the PRA1 family.
SWISS:
9UI14
Gene ID:
10567
Database links:Entrez Gene: 10567Human
Entrez Gene: 14470Mouse
Entrez Gene: 83583Rat
Omim: 604925Human
SwissProt: Q9UI14Human
SwissProt: Q9Z0S9Mouse
SwissProt: O35394Rat
Unigene: 11417Human
Unigene: 22473Mouse
Unigene: 25604Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.