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货号： bs-19872R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19872R
- 英文名称
- Rhodopsin/RP4/RHO
- 中文名称
- 视网膜色素变性蛋白4抗体
- 别 名
- CSNBAD1; MGC138309; MGC138311; OPN 2; OPN2; opsd; OPSD_HUMAN; Opsin 2; opsin 2; Opsin 2 rod pigment; Opsin-2; Opsin2; Retinitis Pigmentosa 4; Retinitis pigmentosa 4 autosomal dominant; RHO; Rhodopsin; RP 4; RP4.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Rhodopsin/RP4/RHO:301-348/348
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008]
Function:
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
Subcellular Location:
Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
Tissue Specificity:
Rod shaped photoreceptor cells which mediates vision in dim light.
Post-translational modifications:
Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
DISEASE:
Retinitis pigmentosa 4.
Night blindness, congenital stationary, autosomal dominant 1.
Similarity:
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Contains one covalently linked retinal chromophore.
SWISS:
P08100
Gene ID:
6010
Database links:Entrez Gene: 509933Cow
Entrez Gene: 493763Dog
Entrez Gene: 6010Human
Entrez Gene: 212541Mouse
Entrez Gene: 24717Rat
Omim: 180380Human
SwissProt: Q95KU1Cat
SwissProt: P28681 Chinese Hamster
SwissProt: P02699Cow
SwissProt: P32308Dog
SwissProt: P08100Human
SwissProt: P15409Mouse
SwissProt: P49912Rabbit
SwissProt: P51489Rat
Unigene: 247565Human
Unigene: 2965Mouse
Unigene: 406156Mouse
Unigene: 92530Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.