Thrombin Activity Fluorometric Assay Kit
货号:
K373-100 基本售价:
6915.5 元 规格:
100assays
产品信息
概述货号 | K373-100 |
描述 | Thrombin enzyme (Factor IIa, EC 3.4.21.5), a Serine protease, is an important clotting factor in the coagulation cascade that involves the conversion of soluble fibrinogen to insoluble active fibrin strands. In this pathway, Prothrombin is proteolytically converted into an active Thrombin. Thrombin is also a potent vasoconstrictor and mitogen implicated as a major factor in vasospasm following subarachnoid hemorrhage. Ruptured cerebral aneurysm blood clots around a cerebral artery releases thrombin, which in turn induces acute and prolonged narrowing of the blood vessel, potentially resulting in cerebral ischemia and infarction (stroke). In addition, it is a pro-inflammatory enzyme that may influence the onset and progression of atherosclerosis. Biovisions Thrombin activity assay kit utilizes the ability of Thrombin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence reader. This assay kit is simple, rapid and can detect Thrombin activity as low as 1 ng in samples. |
同种亚型 | Rabbit IgG |
来源宿主 | Rabbit |
性能供应商 | Biovision |
检测类型 | Fluorescence (Ex/Em = 350/450 nm) • Applications - Determine activity of pure Thrombin• Detect the activity of Thrombin in plasma |
样本类型以及上样量 | • Plasma |
产品特色 | • Simple & convenient protocol.• Can detect thrombin activity as low as .• Kit contains all necessary reagents for measuring thrombin activity. |
试剂盒组分 | • Thrombin Dilution Buffer• Thrombin Assay Buffer• Thrombin Enzyme Standard • Thrombin Substrate |
运输条件 | Blue Ice |
存放说明 | -20℃ |