| 货号 | K806-100 |
| 描述 | Renin (EC 3.4.23.15), also known as angiotensinogenase, is an enzyme that participates in the renin-angiotensin system (RAS) which mediates extracellular volume (i.e. blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. In addition to the systemic RAS, locally expressed RAS has been found in the kidney, heart and nervous system. An overactive renin-angiotensin system leads to vasoconstriction and retention of sodium and water, causing hypertension. Renin inhibitors are widely used for the treatment of hypertension. In BioVision’s Rat Renin Activity Assay Kit, Rat Renin and other proteases hydrolyze a FRET substrate resulting in fluorescence at Ex/Em = 328/552 nm. In the presence of a Rat Renin-Specific Inhibitor, hydrolysis of the substrate is due to only the activity of other proteases. The difference between the total activity and the activity in the presence of Rat Renin-Specific Inhibitor gives the Rat Renin Activity in the sample. This rapid, simple & sensitive kit can detect renin activity as low as 0.12 mU recombinant rat renin. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
| 供应商 | Biovision |
| 样本类型以及上样量 | • Crude extracts and purified Recombinant protein • Tissue lysate |
| 试剂盒组分 | • Renin Assay Buffer • Homogenization Buffer • Rat Renin Substrate • Rat Renin (Lyophilized) • Rat Renin Inhibitor (Lyophilized) • EDANS Standard (100 µM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |