Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric)
货号：
K796-100 基本售价：
6310.5 元 规格：
100assays
产品信息
概述| 货号 | K796-100 |
| 描述 | Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. MAO-A can oxidize primary amines such as serotonin and norepinephrine. MAO-A is a mitochondrial-bound enzyme that is ubiquitously expressed throughout the brain and other tissues. It has been implicated in panic, anxiety, and depression. Several MAO-A specific inhibitors such as clorgyline, brofaromine, toloxatone, tetrindole, etc. have been used as antidepressants, but their usage has been limited due to side effects. BioVision’s MAO-A Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-A inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of MAO substrate. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em = 535/587 nm)• Applications - Screening/studying/characterizing MAO-A inhibitors |
| 样本类型以及上样量 | • |
| 产品特色 | • Rapid & sensitive • High-throughput assay to screen/study/characterize potential inhibitors of monoamine oxidase A• Includes Inhibitor Control [Clorgyline] |
| 试剂盒组分 | • MAO-A Assay Buffer• OxiRedTM Probe (in DMSO)• MAO-A Enzyme• MAO-A Substrate • Developer • Inhibitor Control (Clorgyline) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
