Factor XIIIa Activity Assay Kit (Colorimetric)
货号：
K522-100 基本售价：
6189.5 元 规格：
100assays
产品信息
概述| 货号 | K522-100 |
| 描述 | Factor XIII or fibrin stabilizing factor (EC 2.3.2.13) is an enzyme involved in the blood coagulation system that crosslinks fibrin. Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic “A” subunits and two carrier “B” subunits. Factor XIII is activated by thrombin in the presence of calcium which leads to the release of the activation peptide, followed by the dissociation of carrier subunits. The activated Factor XIII (XIIIa) acts on fibrin (Factor Ia) to form γ-glutamyl-Є-lysyl amide cross links between fibrin molecules leading to the formation of an insoluble clot. The deficiency of Factor XIII affects fibrin clot stability and bleeding disorders. BioVisions Factor XIIIa activity assay kit utilizes the transglutaminase activity of factor XIIIa to cross link an amine-containing substrate to glutamine-containing substrate resulting in the loss of ammonia which can be quantitatively measured by a colorimetric assay. The kit is easy-to-use and can detect Factor XIIIa (as low as 0.1 Loewy U) from plasma and purified protein samples. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Colorimetric (Absorbance 340 nm) • Species reactivity - N/A• Applications - Measurement of FXIIIa activity in plasma and purified/crude enzyme preparations |
| 样本类型以及上样量 | • Plasma• Purified enzyme |
| 产品特色 | • Simple, rapid & convenient assay to measure Factor XIIIa• Includes Positive Control and Inhibitor (Iodoacetamide) |
| 试剂盒组分 | • FXIIIa Assay Buffer• FXIIIa Activation Buffer (4X)• FXIIIa Reaction Buffer (4X)• FXIIIa Detection Buffer (2X)• FXIIIa Probe• Human Factor XIIIa (0.5 Loewy U/µl)• NH4Cl Standard (10 mM)• FXIIIa Inhibitor (Iodoacetamide) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
