HDAC3 Inhibitor Screening Kit (Fluorometric)
货号：
K363-100 基本售价：
6189.5 元 规格：
100assays
产品信息
概述| 货号 | K363-100 |
| 描述 | Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC3 Inhibitor screening Kit, HDAC3 and developer will deacetylate and cleave the substrate [Arg-His-Lys-Lys(Ac)-AFC] to release the quenched fluorescent group (AFC), which can be detected at Em/Ex=380/500 nm. In presence of a HDAC3 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput screening of HDAC3 inhibitors. Trichostatin A (TSA) is included as a control inhibitor to compare the efficacy of the test inhibitors. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Em/Ex = 380/500 nm) • Sample type- Testing candidate HDAC3 inhibitors • Applications- Suitable for high throughput screening of HDAC3 inhibitors |
| 产品特色 | • Simple procedure; takes ~ 60 min • Fast and convenient • Kit contains the necessary reagents for testing putative HDAC3 inhibitors |
| 试剂盒组分 | • HDAC3 Assay Buffer • HDAC3 Substrate • HDAC3 Enzyme • Developer • Trichostatin A |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
