MMP-3 Inhibitor Screening Kit (Fluorometric)
货号：
K793-100 基本售价：
6068.5 元 规格：
100assays
产品信息
概述| 货号 | K793-100 |
| 描述 | The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In BioVision’s MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Ex/Em=325/393 nm. The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition. In addition, we also offer a human recombinant MMP-3 enzyme (Biovision #7783) and a MMP-3 Activity Assay Kit (Biovision #K783-100), separately. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em 325/393 nm) • Sample type- Test inhibitors for MMP-3 • Applications- The kit can be used to screen inhibitors of MMP-3 |
| 产品特色 | • Simple procedure; takes ~ 35-45 minutes • Fast and convenient • The assay is simple, reliable and ensures accuracy and consistency when working with multiple samples |
| 试剂盒组分 | • MMP-3 Assay Buffer • MMP-3 Substrate • MMP-3 Enzyme (lyophilized) • Inhibitor Control (0.1 mM GM6001) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
