| 货号 | K845-100 |
| 描述 | Human Immunodeficiency Virus (HIV) is the cause of the Acquired Immunodeficiency Syndrome (AIDS). Infection with HIV-2 virus causes immunosuppression, as well as AIDS, characterized by the same signs, symptoms and opportunistic infections as HIV-1. However, HIV-2-associated AIDS may often be associated with lower viral load levels than HIV-1. Aspartyl HIV-2 Protease (retropepsin) is an essential enzyme for the life-cycle of HIV virus. Expressed as a part of the Gag-Pol polyprotein complex in the infected cells, it is auto-catalytically released upon formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure. BioVision’s HIV-2 Protease Activity assay kit utilizes the ability of active HIV-2 Protease to cleave a synthetic peptide substrate to release the free fluorophore which can be easily quantified (Ex/Em = 330/450 nm) using a fluorometer or fluorescence microplate reader. This assay is simple, rapid and can detect HIV-2 protease activity in samples and of purified enzyme. |
| 同种亚型 | rabbit IgG |
| 来源宿主 | Rabbit |
| 供应商 | Biovision |
| 样本类型以及上样量 | • Proteins/lysates |
| 试剂盒组分 | • HIV-2 Protease Assay Buffer • HIV-2 Protease Dilution Buffer • HIV-2 Protease Substrate • HIV-2 Protease (Positive Control) • Fl. Standard (10 mM in DMSO) |
| 运输条件 | Dry Ice |
| 存放说明 | -80℃ |
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