Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric)
货号：
K227-100 基本售价：
5584.5 元 规格：
100assays
产品信息
概述| 货号 | K227-100 |
| 描述 | Angiotensin I converting enzyme (ACE1, EC: 3.4.15.1), a dipeptidyl carboxypeptidase, is part of the renin-angiotensin system (RAS) that controls regulation of blood pressure by cleaving the C-terminal dipeptides of angiotensin I and bradykinin. It is found on the luminal surface of vascular endothelial cells, especially in pulmonary tissues. Elevated levels of ACE1 are found in patients suffering from sarcoidosis, leprosy, hyperthyroidism, acute hepatitis, primary biliary cirrhosis, diabetes mellitus, multiple myeloma, osteoarthritis, amyloidosis, Gaucher’s disease, pneumoconiosis, histoplasmosis and miliary tuberculosis. BioVision’s ACE1 Activity Assay Kit utilizes an active ACE1 to cleave a synthetic o-aminobenzoyl peptide (Abz-based peptide) substrate to release a fluorophore. The released Abz can be easily quantified using a fluorescence microplate reader. This assay kit is simple, rapid and can detect ACE activity as low as 10 mU in biological samples. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorometric (Ex/Em = 330/430 nm)• Species reactivity - Mammalian• Applications - Detection of ACE1 activity in tissue/cell lysates |
| 样本类型以及上样量 | • Mammalian tissues: lung, heart, kidney• Serum, plasma |
| 产品特色 | • Simple one-step reaction• Takes only 1-2 hrs• Non-radiometric fluorescent detection• HTP adaptable |
| 试剂盒组分 | • ACE1 Assay Buffer• ACE1 Lysis Buffer• ACE1 Dilution Buffer• ACE1 Positive Control• ACE1 Substrate• Abz-Standard (1 mM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
