MMP-3 Activity Fluorometric Assay Kit
货号：
K783-100 基本售价：
5100.5 元 规格：
100assays
产品信息
概述| 货号 | K783-100 |
| 描述 | The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In BioVision’s MMP-3 Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Ex/Em=325/393 nm. The kit provides a rapid, simple, sensitive and reliable test which can also be used as a high throughput assay of MMP-3 activity. The assay sensitivity is < 50 µU. This kit can be used with our MMP-3 inhibitor, GM6001 (Biovision #1799) as a control. In addition, we also offer a human recombinant MMP-3 enzyme (Biovision #7783) and a MMP-3 inhibitor Screening Kit (Biovision #K793), separately. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em 325/393 nm)• Sample type- Cell and Tissue culture supernatants, urine, plasma and serum, as well as many other biological fluids, growth medium, food etc. • Species reactivity- Mammalian• Applications- The assay |
| 产品特色 | • Simple procedure; takes ~ 60 minutes• Fast and convenient • Sensitive assays for measuring MMP-3 in various biological samples |
| 试剂盒组分 | • MMP-3 Assay Buffer• MMP-3 Substrate • Mca Standard (1mM) • MMP-3 Positive Control |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
