Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric)
货号：
K897-100 基本售价：
4979.5 元 规格：
100assays
产品信息
概述| 货号 | K897-100 |
| 描述 | Angiotensin II converting enzyme (ACE2, EC 3.4.17.23), a zinc-based metalloprotease, is part of the renin-angiotensin system (RAS) that controls the regulation of blood pressure by cleaving the C-terminal dipeptide of Angiotensin II to convert it into Angiotensin 1-7. ACE2 is a receptor of human coronaviruses, such as SARS and HCoV-NL63. It is expressed on the vascular endothelial cells of lung, kidney and heart. ACE2 is a potential therapeutic target for cardiovascular and coronavirus-induced diseases. BioVision’s ACE2 Activity Assay Kit kit will help the research progress in this field. This kit utilizes the ability of an active ACE2 to cleave a synthetic MCA based peptide substrate to release a free fluorophore. The released MCA can be easily quantified using a fluorescence microplate reader. We also provide an ACE2 specific inhibitor that can differentiate the ACE2 activity from other proteolytic activity.The kit can detect as low as 0.4 mU. Our assay kit is simple and can be used in a high-throughput format |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorometric (Ex/Em = 320/420 nm)• Species reactivity - Mammalian• Applications - Detection of ACE2 activity in tissue/cell lysates and enzyme preparations |
| 样本类型以及上样量 | • Mammalian tissues: lung, heart, kidney |
| 产品特色 | • Simple one-step reaction• Takes only 1-2 hrs• Non-radiometric fluorescent detection• HTP adaptable |
| 试剂盒组分 | • ACE Assay Buffer• ACE2 Dilution Buffer• ACE2 Lysis Buffer • ACE2 Positive Control• ACE2 SubstrateACE2 Inhibitor (22 mM)• MCA-Standard (1 mM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
