HDAC8 Activity Fluorometric Assay Kit
货号：
K348-100 基本售价：
4858.5 元 规格：
100assays
产品信息
概述| 货号 | K348-100 |
| 描述 | Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. HDACs are transcriptional repressors with crucial roles in mammalian development. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC8 activity Kit, HDAC8 deacetylates the substrate (R-H-K(Ac)-K(Ac)-AFC) followed by an enzymatic cleavage to release the quenched fluorescent group (AFC), which can be detected at Em/Ex = 380/500 nm. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput measurement of HDAC8 activity in purified, immunoprecipitated and recombinant or genetically modified HDAC8 samples. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Em/Ex = 380/500 nm) • Sample type- Cell and Tissue lysates, plasma and serum, other biological fluids • Species reactivity- Mammalian • Applications- Suitable for high throughput measurement of HDAC8 activity in purifie |
| 产品特色 | • Simple procedure; takes ~ 60 min • Fast and convenient • Kit contains the necessary reagents for accurate measurement of HDAC8 activity |
| 试剂盒组分 | • HDAC8 Assay Buffer • HDAC8 Substrate • HDAC8 Positive Control • AFC Standard (1 mM) • Developer • Trichostatin A (10 µM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
