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货号： bs-5933R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5933R-Cy5.5
- 英文名称
- Anti-KCNK9/Cy5.5
- 中文名称
- Cy5.5标记的TWIK相关酸敏感钾离子通道蛋白9抗体
- 别 名
- KCNK 9; KCNK-9; TASK3; Potassium channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Short=Two pore K(+) channel KT3.2; KCNK9_HUMAN
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 神经生物学 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 40kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KCNK9
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons membrane potential and in resting K+ currents.
Function:
pH-dependent, voltage-insensitive, background potassium channel protein.
Subcellular Location:
Membrane; Multi-pass membrane protein
Tissue Specificity:
Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.
DISEASE:
Defects in KCNK9 are the cause of Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292]. A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism.
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8)
Database links:Entrez Gene: 428382 Chicken
Entrez Gene: 51305 Human
Omim: 605874 Human
SwissProt: Q9NPC2 Human
Unigene: 493037 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.