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货号： bs-4684R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4684R-Cy5.5
- 英文名称
- Anti-Mammaglobin A/Cy5.5
- 中文名称
- Cy5.5标记的乳腺珠蛋白1抗体
- 别 名
- Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretoglobin Family 2A Member 2; SG2A2; UGB 2; UGB2; Uteroglobin; Psbpc3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 8.4kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse Mammaglobin A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Tissue Specificity:
Mammary gland specific. Over-expressed in breast cancer.
Similarity:
Belongs to the secretoglobin family. Lipophilin subfamily.
Database links:Entrez Gene: 4250 Human
Entrez Gene: 100040203 Mouse
Entrez Gene: 361725 Rat
Omim: 605562 Human
SwissProt: Q13296 Human
Unigene: 46452 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乳腺球蛋白是一个乳腺相关糖蛋白，它是一个分泌素家族（包括子宫球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。