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货号: bs-19647R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-19647R
- 英文名称
- Opticin
- 中文名称
- Opticin蛋白抗体
- 别 名
- Oculoglycan; OPT; OPT_HUMAN; OPTC; Opticin.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 37kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Opticin:201-300/332
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008]
Function:
Binds collagen fibrils.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.Entrez Gene: 26254 HumanEntrez Gene: 269120 MouseEntrez Gene: 304802 RatOmim: 605127 HumanSwissProt: Q9UBM4 HumanSwissProt: Q920A0 MouseUnigene: 632468 HumanUnigene: 59985 Mouse
Tissue Specificity:
Retina, iris, ligament, skin and fetal liver.
Post-translational modifications:
O-glycosylated.
Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class III subfamily.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
SWISS:
Q9UBM4
Gene ID:
26254
Database links:Entrez Gene: 26254Human
Entrez Gene: 269120Mouse
Entrez Gene: 304802Rat
Omim: 605127Human
SwissProt: Q9UBM4Human
SwissProt: Q920A0Mouse
Unigene: 632468Human
Unigene: 59985Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.