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货号： bs-19635R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-19635R
- 英文名称
- SEP15
- 中文名称
- 硒蛋白SEP15抗体
- 别 名
- 15 kDa selenoprotein; Sep15; SEP15_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Zebrafish, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 15kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SEP15:101-162/162
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum.
Subcellular Location:
Endoplasmic reticulum lumen. The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum.
Tissue Specificity:
Higher levels in prostate and thyroid gland.
Similarity:
Belongs to the selenoprotein M/SEP15 family.
SWISS:
O60613
Gene ID:
9403
Database links:Entrez Gene: 614360Cow
Entrez Gene: 9403Human
Entrez Gene: 93684Mouse
Entrez Gene: 100038009Pig
Entrez Gene: 113922Rat
Entrez Gene: 352923Zebrafish
Omim: 606254Human
SwissProt: A8YXY3Cow
SwissProt: O60613Human
SwissProt: Q9ERR7Mouse
SwissProt: A1Z623Pig
SwissProt: Q923V8Rat
SwissProt: Q802F3Zebrafish
Unigene: 362728Human
Unigene: 29812Mouse
Unigene: 1124Rat
Unigene: 11333Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.