产品中心
当前位置：首页>产品中心Anti-FEM1A/Cy5.5
货号： bs-6861R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6861R-Cy5.5
- 英文名称
- Anti-FEM1A/Cy5.5
- 中文名称
- Cy5.5标记的前列腺素E受体4相关蛋白抗体
- 别 名
- EPRAP; Fem-1 homolog a (C. elegans); Fem1 homolog a; FEM1-alpha-A; FEM1a-A; Fem1aa; Feminization 1 homolog a (C. elegans); Feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; Protein fem-1 homolog A-A; FEM1A_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 74kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FEM1A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FEM1A is a caspase substrate homologous to the C. Elegans sex determining protein, FEM-1. Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Overexpression of FEM1A in mammalian cells is reported to induce apoptosis.
Function:
Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4.
Subunit:
Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4.
Subcellular Location:
Cytoplasm (Probable).
Tissue Specificity:
Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).
Similarity:
Belongs to the fem-1 family.
Contains 9 ANK repeats.
Contains 2 TPR repeats.
Database links:Entrez Gene: 516550 Cow
Entrez Gene: 55527 Human
Entrez Gene: 14154 Mouse
Entrez Gene: 316131 Rat
GenBank: NP_061178.1 Human
SwissProt: Q29RM5 Cow
SwissProt: Q9BSK4 Human
SwissProt: Q8C4V3 Mouse
SwissProt: Q4V890 Rat
Unigene: 515082 Human
Unigene: 290813 Mouse
Unigene: 228392 Rat
Unigene: 97265 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.