Rat IFN-gamma ELISpot Kit (1 KT)【科瑞奥博】

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Rat IFN-gamma ELISpot Kit (1 KT)

货号： EL585 基本售价： 4530.9 元规格： 1 Kit

产品信息

概述
货号	EL585
别名	IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
全称	Interferon gamma
反应种属	Rat
目标/特异性	Please see the product datasheet

性能
供应商	R&D Systems
检测类型	Quantitative Sandwich ELISA
Entrez Gene IDs	3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70. Authors: Shevtsov M, Pozdnyakov A, Mikhrina A, Yakovleva L, Nikolaev B, Dobrodumov A, Komarova E, Meshalkina D, Ischenko A, Pitkin E, Guzhova I, Margulis B Int J Cancer, 2014;135(9):2118-28. Species: Rat Sample Type: Whole Cells Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen. Authors: King GD, Muhammad AK, Larocque D Mol. Ther., 2011;19(10):1793-801. Species: Rat Sample Type: Whole Cells Steady-state migrating intestinal dendritic cells induce potent inflammatory responses in naive CD4+ T cells. Authors: Milling SW, Jenkins CD, Yrlid U, Cerovic V, Edmond H, McDonald V, Nassar M, Macpherson G Mucosal Immunol, 2009;2(2):156-65. Species: Rat Sample Type: Whole Cells Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Authors: Grundtner R, Dornmair K, Dahm R, Flugel A, Kawakami N, Zeitelhofer M, Schoderboeck L, Nosov M, Selzer E, Willheim M, Kiebler M, Wekerle H, Lassmann H, Bradl M Neurobiol. Dis., 2007;28(3):261-75. Species: Rat Sample Type: Whole Cells Comparative analysis of the fate of donor dendritic cells and B cells and their influence on alloreactive T cell responses under tacrolimus immunosuppression. Authors: Azhipa O, Kimizuka K, Nakao A, Toyokawa H, Okuda T, Neto JS, Alber SM, Kaizu T, Thomson AW, Demetris AJ, Murase N Clin. Immunol., 2005;114(2):199-209. Species: Rat Sample Type: Whole Cells The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Authors: Kawakami N, Lassmann S, Li Z, Odoardi F, Ritter T, Ziemssen T, Klinkert WE, Ellwart JW, Bradl M, Krivacic K, Lassmann H, Ransohoff RM, Volk HD, Wekerle H, Linington C, Flugel A J. Exp. Med., 2004;199(2):185-97. Species: Rat Sample Type: Whole Cells
背景	IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
运输条件	Blue Ice
存放说明	4℃