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Mouse IFN-gamma ELISpot Kit (1 KT)

货号: EL485 基本售价: 询价 规格: 1 Kit

产品信息

概述
货号EL485
别名
IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
全称Interferon gamma
反应种属Mouse
目标/特异性Please see the product datasheet
是否允许进口
是否危险品
性能
供应商R&D Systems
检测类型Quantitative Sandwich ELISA
Entrez Gene IDs3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline);
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Transient Expression of Transgenic IL-12 in Mouse Liver Triggers Unremitting Inflammation Mimicking Human Autoimmune Hepatitis
J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells

HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity.
Authors: Kanagavelu, Saravana, Termini, James M, Gupta, Sachin, Raffa, Francesc, Fuller, Katherin, Rivas, Yaelis, Philip, Sakhi, Kornbluth, Richard, Stone, Geoffrey
PLoS ONE, 2014;9(2):e90100.
Species: Mouse
Sample Type: Whole Cells

Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus.
Authors: Lv L, Li X, Liu G, Li R, Liu Q, Shen H, Wang W, Xue C, Cao Y
J Vet Sci, 2014;15(2):209-16.
Species: Mouse
Sample Type: Whole Cells

A VLP vaccine induces broad-spectrum cross-protective antibody immunity against H5N1 and H1N1 subtypes of influenza A virus.
Authors: Wu, Chia-Yin, Yeh, Yi-Chun, Chan, Jia-Tsro, Yang, Yu-Chih, Yang, Ji-Rong, Liu, Ming-Tsa, Wu, Ho-Sheng, Hsiao, Pei-Wen
PLoS ONE, 2012;7(8):e42363.
Species: Mouse
Sample Type: Whole Cells

Novel immunocompetent murine tumor model for evaluation of conditionally replication-competent (oncolytic) murine adenoviral vectors.
Authors: Robinson M, Li B, Ge Y, Ko D, Yendluri S, Harding T, VanRoey M, Spindler KR, Jooss K
J. Virol., 2009;83(8):3450-62.
Species: Mouse
Sample Type: Whole Cells

Elicitation of broad CTL response against HIV-1 by the DNA vaccine encoding artificial multi-component fusion protein MultiHIV--study in domestic pigs.
Authors: Molder T, Adojaan M, Kaldma K, Ustav M, Sikut R
Vaccine, 2009;28(2):293-8.
Species: Mouse
Sample Type: Whole Cells

Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection.
Authors: Zhu Q, Thomson CW, Rosenthal KL, McDermott MR, Collins SM, Gauldie J
Mucosal Immunol, 2008;1(1):78-88.
Species: Mouse
Sample Type: Whole Cells

NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Authors: Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
J. Immunol., 2008;181(10):7157-65.
Species: Mouse
Sample Type: Whole Cells

Type I IFNs play a role in early resistance, but subsequent susceptibility, to the African trypanosomes.
Authors: Lopez R, Demick KP, Mansfield JM, Paulnock DM
J. Immunol., 2008;181(7):4908-17.
Species: Mouse
Sample Type: Whole Cells

Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy.
Authors: Yang J, Popoola J, Khandwala S, Vadivel N, Vanguri V, Yuan X, Dada S, Guleria I, Tian C, Ansari MJ, Shin T, Yagita H, Azuma M, Sayegh MH, Chandraker A
Circulation, 2008;117(5):660-9.
Species: Mouse
Sample Type: Whole Cells

Nitric oxide mediates T cell cytokine production and signal transduction in histidine decarboxylase knockout mice.
Authors: Koncz A, Pasztoi M, Mazan M, Fazakas F, Buzas E, Falus A, Nagy G
J. Immunol., 2007;179(10):6613-9.
Species: Mouse
Sample Type: Whole Cells

One-year Expression From High-capacity Adenoviral Vectors in the Brains of Animals With Pre-existing Anti-adenoviral Immunity: Clinical Implications.
Authors: Barcia C, Jimenez-Dalmaroni M, Kroeger KM, Puntel M, Rapaport AJ, Larocque D, King GD, Johnson SA, Liu C, Xiong W, Candolfi M, Mondkar S, Ng P, Palmer D, Castro MG, Lowenstein PR
Mol. Ther., 2007;15(12):2154-2163.
Species: Mouse
Sample Type: Whole Cells

Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
Authors: Kurooka M, Kaneda Y
Cancer Res., 2007;67(1):227-36.
Species: Mouse
Sample Type: Whole Cells

Elicitation of immunity to HIV type 1 Gag is determined by Gag structure.
Authors: Young KR, Ross TM
AIDS Res. Hum. Retroviruses, 2006;22(1):99-108.
Species: Mouse
Sample Type: Whole Cells
Application: ELISpot Development
Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs.
Authors: Wang D, Li Y, Yu D, Song SS, Kandimalla ER, Agrawal S
Int. J. Oncol., 2004;24(4):901-8.
Species: Mouse
Sample Type: Whole Cells

背景IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
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