| 货号 | XEL2906 |
| 别名 | CSPB; CTLA-1; CTSGL1; Fragmentin-2; Granzyme B; Granzyme-2; GRB; GrzB; GZMB; HLP; SECT |
| 反应种属 | Human |
| 目标/特异性 | Please see the product datasheet |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | R&D Systems |
| 检测类型 | Quantitative Sandwich ELISA |
| Entrez Gene IDs | 3002 (Human); 14939 (Mouse); |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. SHP-2 expression negatively regulates NK cell function. | |
| 背景 | Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |