R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5 PLoS ONE, 2016;11(8):e0160875. Species: Human Sample Type: Cell Culture Supernates
Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type-Specific Manner Authors: M Tatematsu, R Yoshida, Y Morioka, N Ishii, K Funami, A Watanabe, K Saeki, T Seya, M Matsumoto J Immunol, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production Proc Natl Acad Sci USA, 2016;113(38):10625-10630. Species: Human Sample Type: Cell Culture Supernates
A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer. Authors: Hosein A, Livingstone J, Buchanan M, Reid J, Hallett M, Basik M BMC Cancer, 2015;15(0):130. Species: Human Sample Type: Cell Culture Supernates
NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection. Authors: Ranjan P, Singh N, Kumar A, Neerincx A, Kremmer E, Cao W, Davis W, Katz J, Gangappa S, Lin R, Kufer T, Sambhara S Eur J Immunol, 2015;45(3):758-72. Species: Human Sample Type: cell supernates
High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus. Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M J Virol, 2015;89(7):3859-69.
Induction and Antagonism of Antiviral Responses in Respiratory Syncytial Virus-Infected Pediatric Airway Epithelium. Authors: Villenave R, Broadbent L, Douglas I, Lyons J, Coyle P, Teng M, Tripp R, Heaney L, Shields M, Power U J Virol, 2015;89(24):12309-18. Species: Human Sample Type: Cell Culture Supernates
Natural killer cells can inhibit the transmission of human cytomegalovirus in cell culture by using mechanisms from innate and adaptive immune responses. Authors: Wu Z, Sinzger C, Reichel J, Just M, Mertens T J Virol, 2015;89(5):2906-17. Species: Human Sample Type: Cell Culture Supernates
The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-beta during Chlamydia trachomatis infection. Authors: Zhang Y, Yeruva L, Marinov A, Prantner D, Wyrick P, Lupashin V, Nagarajan U J Immunol, 2014;193(5):2394-404. Species: Human Sample Type: cell supernates
Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. Authors: Xia, Mao, Gonzalez, Patrick, Li, Chunyan, Meng, Gang, Jiang, Aiqin, Wang, Hongwei, Gao, Qian, Debatin, Klaus-Mi, Beltinger, Christia, Wei, Jiwu J Virol, 2014;88(9):5152-64. Species: Human Sample Type: Cell Culture Supernates
HSV-2 increases TLR4-dependent phosphorylated IRFs and IFN-beta induction in cervical epithelial cells. Authors: Liu H, Chen K, Feng W, Guo J, Li H PLoS ONE, 2014;9(4):e94806.
Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. Authors: Stone, Amy E L, Giugliano, Silvia, Schnell, Gretja, Cheng, Linling, Leahy, Katelyn, Golden-Mason, Lucy, Gale, Michael, Rosen, Hugo R PLoS Pathog, 2013;9(4):e1003316. Species: Human Sample Type: cell culture supernate
Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry. Authors: Osterlund P, Strengell M, Sarin L, Poranen M, Fagerlund R, Melen K, Julkunen I J Virol, 2012;86(20):11183-93. Species: Human Sample Type: Cell Culture Supernates
Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol. Authors: Patel MV, Ghosh M, Fahey JV, Wira CR PLoS ONE, 2012;7(4):e35654. Species: Human Sample Type: Cell Culture Supernates
Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Authors: Liang X, Moseman EA, Farrar MA Blood, 2010;115(24):5041-52. Species: Human Sample Type: Cell Culture Supernates
Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I. Authors: Wang P, Arjona A, Zhang Y Nat. Immunol., 2010;11(10):912-9. Species: Mouse Sample Type: Plasma
Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Authors: Chase JC, Celli J, Bosio CM Infect. Immun., 2009;77(1):180-95. Species: Human Sample Type: Cell Culture Supernates
Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans. Authors: Schirmer SH, van Royen N, Moerland PD, Fledderus JO, Henriques JP, van der Schaaf RJ, Vis MM, Baan J, Koch KT, Horrevoets AJ, Hoefer IE, Piek JJ J. Am. Coll. Cardiol., 2009;53(23):2141-7. Species: Human Sample Type: Plasma
The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3. Authors: Lee SH, Kim JS, Jun HK J. Immunol., 2009;182(9):5823-35. Species: Human Sample Type: Cell Lysates
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. Authors: Beck LA, Boguniewicz M, Hata T, Schneider LC, Hanifin J, Gallo R, Paller AS, Lieff S, Reese J, Zaccaro D, Milgrom H, Barnes KC, Leung DY J. Allergy Clin. Immunol., 2009;124(2):260-9, 269.e1. Species: Human Sample Type: Serum
Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling. Authors: Lee MT, Hooper LC, Kump L, Hayashi K, Nussenblatt R, Hooks JJ, Detrick B Clin. Exp. Immunol., 2007;147(1):71-80. Species: Human Sample Type: Serum
Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression. Authors: Newcomb DC, Sajjan US, Nagarkar DR, Goldsmith AM, Bentley JK, Hershenson MB Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(4):L1021-8. Species: Human Sample Type: Cell Culture Supernates
APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA. Authors: Schmidt KN, Leung B, Kwong M, Zarember KA, Satyal S, Navas TA, Wang F, Godowski PJ J. Immunol., 2004;172(1):138-43. Species: Human Sample Type: Cell Culture Supernates
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. Authors: Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M J. Gen. Virol., 2004;85(0):2603-13. Species: Human Sample Type: Cell Culture Supernates
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