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Human sVCAM-1/CD106 Quantikine SixPak (6 Plates) (1 PK)

货号: SVC00 基本售价: 32598.9 元 规格: 1 PACK

产品信息

概述
货号SVC00
描述The Quantikine Human sVCAM-1 Immunoassay is a 2 hour solid-phase ELISA designed to measure human sVCAM-1 in cell culture supernates, serum, and plasma. It contains CHO cell-expressed recombinant human sVCAM-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human sVCAM-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring sVCAM-1.
别名CD106 antigen; CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; VCAM-1;
全称
Vascular Cell Adhesion Molecule 1
反应种属Human
目标/特异性Natural and recombinant human sVCAM-1
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
7412 (Human); 22329 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Splenic pooling and loss of VCAM-1 causes an engraftment defect in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation
Haematologica, 2016;0(0):.
Species: Human
Sample Type: Serum

Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia
PLoS ONE, 2016;11(9):e0162652.
Species: Human
Sample Type: Plasma

Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection
Authors: M Kulkarni, E Bowman, J Gabriel, T Amburgy, E Mayne, DA Zidar, C Maierhofer, AN Turner, JA Bazan, SL Koletar, MM Lederman, SF Sieg, NT Funderburg
Open Forum Infect Dis, 2016;3(4):ofw224.
Species: Human
Sample Type: Plasma

Interrelationship of Multiple Endothelial Dysfunction Biomarkers with Chronic Kidney Disease.
Authors: Chen J, Hamm L, Mohler E, Hudaihed A, Arora R, Chen C, Liu Y, Browne G, Mills K, Kleinpeter M, Simon E, Rifai N, Klag M, He J
PLoS ONE, 2015;10(7):e0132047.
Species: Human
Sample Type: Serum

Kidney function, endothelial activation and atherosclerosis in black and white Africans with rheumatoid arthritis.
Authors: Dessein, Patrick, Hsu, Hon-Chun, Tsang, Linda, Millen, Aletta M, Woodiwiss, Angela J, Norton, Gavin R, Solomon, Ahmed, Gonzalez-Gay, Miguel A
PLoS ONE, 2015;10(3):e0121693.
Species: Human
Sample Type: Plasma

Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy.
Authors: Abu El-Asrar, Ahmed M, Nawaz, Mohd Imt, Mohammad, Ghulam, Siddiquei, Mohammad, Alam, Kaiser, Mousa, Ahmed, Opdenakker, Ghislain
Lipids Health Dis, 2014;13(0):187.
Species: Human
Sample Type: Vitreous Humor

Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome.
Authors: Tuttolomondo A, Pecoraro R, Di Raimondo D, Di Sciacca R, Canino B, Arnao V, Butta C, Della Corte V, Maida C, Licata G, Pinto A
Diabetol Metab Syndr, 2014;6(1):28.
Species: Human
Sample Type: Plasma

Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer.
Authors: Miles D, de Haas S, Dirix L, Romieu G, Chan A, Pivot X, Tomczak P, Provencher L, Cortes J, Delmar P, Scherer S
Br J Cancer, 2013;108(5):1052-60.
Species: Human
Sample Type: Plasma

Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells.
Authors: Calicchio R, Buffat C, Mathieu J, Ben Salem N, Mehats C, Jacques S, Hertig A, Berkane N, Grevoul-Fresquet J, Simeoni U, Peyssonnaux C, Gavard J, Vaiman D, Miralles F
Am J Pathol, 2013;183(6):1993-2006.
Species: Human
Sample Type: Plasma

Plasma concentrations predict aortic expression of growth-arrest-specific protein 6 in patients undergoing coronary artery bypass grafting.
Authors: Lee, Chien-Hs, Shieh, Yi-Shing, Tsai, Chien-Su, Hung, Yi-Jen, Tsai, Yi-Ting, Lin, Chih-Yua
PLoS ONE, 2013;8(11):e79452.
Species: Human
Sample Type: Plasma

Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.
Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
Cytokine, 2013;61(3):755-8.
Species: Human
Sample Type: Serum

Cerebrospinal Fluid Neopterin as Marker of the Meningo-Encephalitic Stage of Trypanosoma brucei gambiense Sleeping Sickness.
Authors: Tiberti N, Hainard A, Lejon V, Courtioux B, Matovu E, Enyaru JC, Robin X, Turck N, Kristensson K, Ngoyi DM, Vatunga GM, Krishna S, Buscher P, Bisser S, Ndungu JM, Sanchez JC
PLoS ONE, 2012;7(7):e40909.
Species: Human
Sample Type: CSF

Mechanisms of endothelial dysfunction in resistance arteries from patients with end-stage renal disease.
Authors: Luksha L, Stenvinkel P, Hammarqvist F, Carrero JJ, Davidge ST, Kublickiene K
PLoS ONE, 2012;7(4):e36056.
Species: Human
Sample Type: Serum

Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study.
Authors: Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, Nathan BM, Deering MM, Schwartz BL, Abuzzahab MJ, Gandrud LM, Moran A, Billington CJ, Schwarzenberg SJ
Obesity (Silver Spring), 2012;20(2):364-70.
Species: Human
Sample Type: Plasma

Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis.
BMC Infect Dis, 2012;12(0):144.
Species: Human
Sample Type: Serum

Endogenous granulocyte colony-stimulating factor: a biomarker in acute ischemic stroke.
Authors: Yu SC, Kuo CL, Huang CS, Chang CS, Wu SL, Su SL, Liu CS
Biomarkers, 2012;17(4):319-24.
Species: Human
Sample Type: Plasma

Evaluation of endothelial function and subclinical atherosclerosis in association with hepatitis C virus in HIV-infected patients: a cross-sectional study.
Authors: Masia M, Padilla S, Robledano C, Ramos J, Gutierrez F
BMC Infect Dis, 2011;11(0):265.
Species: Human
Sample Type: Plasma

Divergent anti-inflammatory effects of different oil acute consumption on healthy individuals.
Authors: Papageorgiou N, Tousoulis D, Psaltopoulou T, Giolis A, Antoniades C, Tsiamis E, Miliou A, Toutouzas K, Siasos G, Stefanadis C
Eur J Clin Nutr, 2011;65(4):514-9.
Species: Human
Sample Type: Serum

Prognostic significance of angiogenic factors in uterine cervical cancer.
Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2589-95.
Species: Human
Sample Type: Serum

Levels of circulating CD45(dim)CD34(+)VEGFR2(+) progenitor cells correlate with outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors.
Authors: Farace F, Gross-Goupil M, Tournay E, Taylor M, Vimond N, Jacques N, Billiot F, Mauguen A, Hill C, Escudier B
Br. J. Cancer, 2011;104(7):1144-50.
Species: Human
Sample Type: Plasma

Influence of a dose-dense adjuvant chemotherapy on sVCAM-1/sICAM-1 serum levels in breast cancer patients with 1-3 positive lymph nodes.
Authors: Eggeman H, Stoblen F, Thill M, Korlach S, Schmid P, Luftner D, Elling D, Taran FA, Kummel S, Landt S
Anticancer Res., 2011;31(8):2617-22.
Species: Human
Sample Type: Serum

Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
Int J Obes (Lond), 2011;35(6):800-9.
Species: Human
Sample Type: Serum

Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.
Authors: Rhind SG, Crnko NT, Baker AJ
J Neuroinflammation, 2010;7(0):5.
Species: Human
Sample Type: Serum

Placenta growth factor in sickle cell disease: association with hemolysis and inflammation.
Authors: Brittain JE, Hulkower B, Jones SK, Strayhorn D, De Castro L, Telen MJ, Orringer EP, Hinderliter A, Ataga KI
Blood, 2010;115(10):2014-20.
Species: Human
Sample Type: Plasma

Plasma protein growth arrest-specific 6 levels are associated with altered glucose tolerance, inflammation, and endothelial dysfunction.
Authors: Hung YJ, Lee CH, Chu NF
Diabetes Care, 2010;33(8):1840-4.
Species: Human
Sample Type: Plasma

SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
Diabetes, 2010;59(4):829-35.
Species: Human
Sample Type: Serum

Effect of intensive lifestyle changes on endothelial function and on inflammatory markers of atherosclerosis.
Authors: Dod HS, Bhardwaj R, Sajja V, Weidner G, Hobbs GR, Konat GW, Manivannan S, Gharib W, Warden BE, Nanda NC, Beto RJ, Ornish D, Jain AC
Am. J. Cardiol., 2010;105(3):362-7.
Species: Human
Sample Type: Serum

Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects.
Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
Atherosclerosis, 2010;210(2):536-41.
Species: Human
Sample Type: Plasma

Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study.
Authors: Jacobs M, van Greevenbroek MM, van der Kallen CJ, Ferreira I, Blaak EE, Feskens EJ, Jansen EH, Schalkwijk CG, Stehouwer CD
Eur. J. Clin. Invest., 2009;39(6):437-44.
Species: Human
Sample Type: Plasma

Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.
Authors: Yearley JH, Xia D, Pearson CB, Carville A, Shannon RP, Mansfield KG
Lab. Invest., 2009;89(6):657-67.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Plasma

Non-conventional markers of atherosclerosis before and after gastric banding surgery.
Authors: Hanusch-Enserer U, Zorn G, Wojta J, Kopp CW, Prager R, Koenig W, Schillinger M, Roden M, Huber K
Eur. Heart J., 2009;30(12):1516-24.
Species: Human
Sample Type: Plasma

Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis.
Authors: Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, Arnao V, Licata G
Atherosclerosis, 2009;203(2):503-8.
Species: Human
Sample Type: Plasma

A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients.
Authors: Plat J, Brufau G, Dallinga-Thie GM, Dasselaar M, Mensink RP
J. Nutr., 2009;139(6):1143-9.
Species: Human
Sample Type: Plasma

HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
AIDS, 2009;23(8):929-39.
Species: Human
Sample Type: Plasma

Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species.
Authors: Tatara Y, Ohishi M, Yamamoto K, Shiota A, Hayashi N, Iwamoto Y, Takeda M, Takagi T, Katsuya T, Ogihara T, Rakugi H
J. Mol. Cell. Cardiol., 2009;47(1):104-11.
Species: Human
Sample Type: Plasma

Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy.
Authors: Little JA, Hauser KP, Martyr SE, Harris A, Maric I, Morris CR, Suh JH, Taylor J, Castro O, Machado R, Kato G, Gladwin MT
Eur. J. Haematol., 2009;82(4):315-21.
Species: Human
Sample Type: Plasma

Immuno-inflammatory predictors of stroke at follow-up in patients with chronic non-valvular atrial fibrillation (NVAF).
Authors: Pinto A, Tuttolomondo A, Casuccio A, Di Raimondo D, Di Sciacca R, Arnao V, Licata G
Clin. Sci., 2009;116(10):781-9.
Species: Human
Sample Type: Plasma

A phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin lymphoma: Southwest oncology group study S0108.
Authors: Stopeck AT, Unger JM, Rimsza LM, Bellamy WT, Iannone M, Persky DO, Leblanc M, Fisher RI, Miller TP
Leuk. Lymphoma, 2009;50(5):728-35.
Species: Human
Sample Type: Plasma

Consumption of isoflavone-rich soy protein does not alter homocysteine or markers of inflammation in postmenopausal women.
Authors: Greany KA, Nettleton JA, Wangen KE, Thomas W, Kurzer MS
Eur J Clin Nutr, 2008;62(0):1419-25.
Species: Human
Sample Type: Serum

Excessive body iron stores are not associated with risk of coronary heart disease in women.
Authors: Sun Q, Ma J, Rifai N, Franco OH, Rexrode KM, Hu FB
J. Nutr., 2008;138(12):2436-41.
Species: Human
Sample Type: Plasma

Association of soluble cell adhesion molecules with ankle-brachial index in a biethnic cohort of predominantly hypertensive individuals.
Authors: Khaleghi M, Ali Z, Mosley TH, Turner ST, Kullo IJ
Clin. Chem., 2008;54(11):1788-95.
Species: Human
Sample Type: Plasma

Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n-3 fatty acid.
Authors: Barcelo-Coblijn G, Murphy EJ, Othman R, Moghadasian MH, Kashour T, Friel JK
Am. J. Clin. Nutr., 2008;88(3):801-9.
Species: Human
Sample Type: Plasma

Effects of weight loss from a very-low-carbohydrate diet on endothelial function and markers of cardiovascular disease risk in subjects with abdominal obesity.
Authors: Keogh JB, Brinkworth GD, Noakes M, Belobrajdic DP, Buckley JD, Clifton PM
Am. J. Clin. Nutr., 2008;87(3):567-76.
Species: Human
Sample Type: Serum

The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alpha-dependent manner in vitro and in vivo in mice.
Authors: Orasanu G, Ziouzenkova O, Devchand PR, Nehra V, Hamdy O, Horton ES, Plutzky J
J. Am. Coll. Cardiol., 2008;52(10):869-81.
Species: Human
Sample Type: Plasma

Physical activity during daily life and circulating biomarker levels in patients with peripheral arterial disease.
Authors: Craft LL, Guralnik JM, Ferrucci L, Liu K, Tian L, Criqui MH, Tan J, McDermott MM
Am. J. Cardiol., 2008;102(9):1263-8.
Species: Human
Sample Type: Plasma

Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers.
Authors: Shariat SF, Karam JA, Walz J, Roehrborn CG, Montorsi F, Margulis V, Saad F, Slawin KM, Karakiewicz PI
Clin. Cancer Res., 2008;14(12):3785-91.
Species: Human
Sample Type: Plasma

An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women.
Authors: Tholstrup T, Raff M, Straarup EM, Lund P, Basu S, Bruun JM
J. Nutr., 2008;138(8):1445-51.
Species: Human
Sample Type: Plasma

Fish oil in combination with high or low intakes of linoleic acid lowers plasma triacylglycerols but does not affect other cardiovascular risk markers in healthy men.
Authors: Damsgaard CT, Frokiaer H, Andersen AD, Lauritzen L
J. Nutr., 2008;138(6):1061-6.
Species: Human
Sample Type: Plasma

Effects of gonadotropin-releasing hormone agonist/recombinant follicle-stimulating hormone versus gonadotropin-releasing hormone antagonist/recombinant follicle-stimulating hormone on follicular fluid levels of adhesion molecules during in vitro fertilization.
Authors: Fornaro F, Cobellis L, Mele D, Tassou A, Badolati B, Sorrentino S, De Lucia D, Colacurci N
Fertil. Steril., 2007;87(1):39-47.
Species: Human
Sample Type: Follicular Fluid

Soluble adhesion molecules and angiotensin-converting enzyme in dementia.
Authors: Nielsen HM, Londos E, Minthon L, Janciauskiene SM
Neurobiol. Dis., 2007;26(1):27-35.
Species: Human
Sample Type: Plasma

Interaction between cytokines and sCD40L in patients with stable and unstable coronary syndromes.
Authors: Tousoulis D, Antoniades C, Nikolopoulou A, Koniari K, Vasiliadou C, Marinou K, Koumallos N, Papageorgiou N, Stefanadi E, Siasos G, Stefanadis C
Eur. J. Clin. Invest., 2007;37(8):623-8.
Species: Human
Sample Type: Serum

Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure.
Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT
Atherosclerosis, 2007;199(1):215-21.
Species: Human
Sample Type: Plasma

Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling.
Authors: Lee MT, Hooper LC, Kump L, Hayashi K, Nussenblatt R, Hooks JJ, Detrick B
Clin. Exp. Immunol., 2007;147(1):71-80.
Species: Human
Sample Type: Serum

Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease.
Authors: Molica S, Vitelli G, Mirabelli R, Digiesu G, Giannarelli D, Cuneo A, Ribatti D, Vacca A
Leuk. Lymphoma, 2006;47(6):1034-40.
Species: Human
Sample Type: Serum

Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome.
Authors: Wang TD, Chen WJ, Cheng WC, Lin JW, Chen MF, Lee YT
Am. J. Cardiol., 2006;98(8):1057-62.
Species: Human
Sample Type: Plasma

Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease.
Authors: Hung MJ, Cherng WJ, Cheng CW, Li LF
Am. J. Cardiol., 2006;97(10):1429-34.
Species: Human
Sample Type: Serum

C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease.
Authors: Makis AC, Hatzimichael EC, Stebbing J, Bourantas KL
Arch. Intern. Med., 2006;166(3):366-8.
Species: Human
Sample Type: Plasma

Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.
Authors: Jensen J, Krakauer M, Sellebjerg F
Cytokine, 2005;29(1):24-30.
Species: Human
Sample Type: Plasma

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景VCAM-1 (Vascular Cell Adhesion Molecule-1; CD106) is a transmembrane molecule that mediates the adhesion of immune cells to the vascular endothelium during inflammation. It binds to several integrins including alpha4/beta1 (VLA-4), alpha4/beta7, alpha9/beta1, and alphaD/beta2. It is expressed constitutively in the bone marrow where it regulates T cell, B cell, and hematopoietic progenitor cell migration. A soluble form VCAM-1 can promote monocyte chemotaxis.
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参考文献
  • Acute Myeloid Leukemia
  • Adhesion Molecules in Angiogenesis
  • Adhesion Molecules on Endothelial Cells
  • Adhesion Molecules on VSMC
  • Adhesive Interactions in Allergy and Asthma
  • Adipose-derived Stem Cell Markers
  • Cancer Biomarkers
  • Endothelial Cell Differentiation Markers
  • Endothelial Cell Markers
  • Endothelial Progenitor and Endothelial Cell Markers
  • Hematopoietic Stem Cell Markers
  • Immunoglobulin Superfamily CAMs
  • Mesenchymal Stem Cell Markers
  • Mouse Tissue-Resident Macrophage Markers