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Human Angiopoietin-1 Quantikine SixPak (6 Plates) (1 PK)

货号: SANG10 基本售价: 32598.9 元 规格: 1 PACK

产品信息

概述
货号SANG10
描述The Quantikine Human Angiopoietin-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Angiopoietin-1 in cell culture supernates, serum, plasma, saliva, and human milk. It contains NS0-expressed recombinant human Angiopoietin-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Angiopoietin-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Angiopoietin-1.
别名AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1; KIAA0003;
反应种属Human
目标/特异性Natural and recombinant human Angiopoietin-1
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
284 (Human); 11600 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Sci Rep, 2016;6(0):29029.
Species: Human
Sample Type: Cell Culture Supernates

Circulating Angiopoietin-1 Is Not a Biomarker of Disease Severity or Prognosis in Pulmonary Hypertension
PLoS ONE, 2016;11(11):e0165982.
Species: Human
Sample Type: Plasma

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1
Sci Adv, 2016;2(4):e1501290.
Species: Human
Sample Type: Cell Lysates

Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
Sci Rep, 2016;6(0):39400.
Species: Human
Sample Type: Serum

EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.
Authors: Nguyen T, Arthur A, Panagopoulos R, Paton S, Hayball J, Zannettino A, Purton L, Matsuo K, Gronthos S
Stem Cells, 2015;33(9):2838-49.
Species: Human
Sample Type: Cell Culture Supernates

Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass.
Authors: Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M
PLoS ONE, 2015;10(8):e0136205.
Species: Human
Sample Type: Plasma

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer.
Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
BMC Cancer, 2014;14(0):696.
Species: Human
Sample Type: Serum

Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia.
Authors: Gomes L, Alves-Junior E, Rodrigues-Jesus C, Nery A, Gasquez-Martin T, Fontes C
PLoS ONE, 2014;9(10):e109246.
Species: Human
Sample Type: Serum

Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.
Proc Natl Acad Sci U S A, 2012;109(25):10024-9.
Species: Primate - Papio cynocephalus (Yellow Baboon)
Sample Type: Serum

Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans.
Authors: Aronis KN, Diakopoulos KN, Fiorenza CG
Diabetologia, 2011;54(9):2358-67.
Species: Human
Sample Type: Serum

CD34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans.
Authors: Sobrino T, Arias S, Perez-Mato M, Agulla J, Brea D, Rodriguez-Yanez M, Castillo J
J. Neurosci. Res., 2011;89(7):979-85.
Species: Human
Sample Type: Serum

Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer.
Authors: Rahbari NN, Schmidt T, Falk CS, Hinz U, Herber M, Bork U, Buchler MW, Weitz J, Koch M
BMC Cancer, 2011;11(0):286.
Species: Human
Sample Type: Serum

Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation.
Authors: Hurliman AK, Speroff L, Stouffer RL, Patton PE, Lee A, Molskness TA
Fertil. Steril., 2010;93(5):1493-9.
Species: Human
Sample Type: Serum

Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF.
Authors: Boucherat O, Franco-Montoya ML, Delacourt C, Martinovic J, Masse V, Elie C, Thebaud B, Benachi A, Bourbon JR
Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(6):L849-56.
Species: Human
Sample Type: Tissue Homogenates

Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts.
Authors: Labonte L, Li Y, Yang L, Gillingham A, Halpenny M, Giulivi A, Sills T, Evans K, Zanke B, Allan DS
Exp. Hematol., 2009;37(6):673-8.
Species: Human
Sample Type: Plasma

Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors.
Authors: Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu IC, Aksu S, Akman U, Ozcebe OI
Ann. Hematol., 2009;88(7):667-71.
Species: Human
Sample Type: Plasma

Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion.
Authors: Shantha Kumara HM, Feingold D, Kalady M, Dujovny N, Senagore A, Hyman N, Cekic V, Whelan RL
Ann. Surg., 2009;249(6):973-7.
Species: Human
Sample Type: Plasma

Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.
Authors: Shim WS, Lim SY, Li SQ, Gu Y, Ong HC, Song IC, Chuah SC, Wong P
J. Mol. Cell. Cardiol., 2008;45(1):70-80.
Species: Porcine
Sample Type: Tissue Homogenates

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008;36(8):1035-46.
Species: Human
Sample Type: Cell Culture Supernates

Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?
Authors: Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF
Ann. Surg., 2008;247(2):320-6.
Species: Human
Sample Type: Plasma

Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis?
Authors: Choudhury A, Freestone B, Patel J, Lip GY
Chest, 2007;132(6):1913-9.
Species: Human
Sample Type: Plasma

Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
Cancer Lett., 2007;248(1):131-6.
Species: Human
Sample Type: Plasma

Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity.
Authors: Anagnostopoulos A, Eleftherakis-Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, Dimopoulos MA, Terpos E
Br. J. Haematol., 2007;137(6):560-8.
Species: Human
Sample Type: Serum

Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy.
Authors: Kanazawa H, Tochino Y, Asai K
J. Allergy Clin. Immunol., 2007;121(2):390-5.
Species: Human
Sample Type: Sputum

Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
Stem Cells, 2007;25(8):1862-71.
Species: Human
Sample Type: Cell Culture Supernates

Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.
Authors: Lee CY, Tien HF, Hu CY, Chou WC, Lin LI
Br. J. Cancer, 2007;97(7):877-82.
Species: Human
Sample Type: Plasma

Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients.
Authors: Caine GJ, Ryan P, Lip GY, Blann AD
Cancer Lett., 2007;251(2):296-301.
Species: Human
Sample Type: Plasma

Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients.
Authors: Kanazawa H, Nomura S, Asai K
Chest, 2007;131(4):1035-41.
Species: Human
Sample Type: Sputum

Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers.
Authors: Niedzwiecki S, Stepien T, Kopec K, Kuzdak K, Komorowski J, Krupinski R, Stepien H
Cytokine, 2006;36(5):291-5.
Species: Human
Sample Type: Serum

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis*
Authors: Ricciuto DR, Dos Santos CC, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, Kain KC, Liaw PC, Liles WC
Crit. Care Med., 0;0(0):.
Species: Human
Sample Type: Plasma

生物活性< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
背景Angiopoietins, Ang-1, Ang-2, and Ang-3 (mouse)/Ang-4 (human), are natural agonists or antagonists of the Tie-2 receptor tyrosine kinase and are important modulators of angiogenesis. Two domains characterize the angiopoietin family of proteins: an N-terminal coiled-coil domain that mediates homo-oligomerization, and a C-terminal fibrinogen-like domain that binds Tie-2.
运输条件Blue Ice
存放说明4℃
参考文献
  • Angiopoietins, Angiopoietin-like Proteins, and Receptors
  • HIF Transcription Factors
  • Inflammatory Mediators