R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors. Authors: Zhong H, Davis A, Ouzounova M, Carrasco R, Chen C, Breen S, Chang Y, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice D, Clouthier S, Xiao Z, Wicha M, Korkaya H, Hollingsworth R Cancer Res, 2016;76(2):480-90. Species: Human Sample Type: Cell Culture Supernates
IL-6 trans-signaling is another pathway to upregulate Osteopontin Cytokine, 2016;90(0):88-95. Species: Human Sample Type: Cell culture supernatant
Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: the Osteoporotic Fractures in Men (MrOS) J Bone Miner Res, 2016;0(0):. Species: Human Sample Type: Serum
Prevalent peripheral arterial disease and inflammatory burden BMC Geriatr, 2016;16(1):213. Species: Human Sample Type: Serum
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFalpha-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. Authors: Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, Yamori T, Shibasaki M, Nomoto A PLoS ONE, 2015;10(3):e0119415. Species: Human Sample Type: Cell Culture Supernates
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma. Authors: Tai Y, Chang B, Kong S, Fulciniti M, Yang G, Calle Y, Hu Y, Lin J, Zhao J, Cagnetta A, Cea M, Sellitto M, Zhong M, Wang Q, Acharya C, Carrasco D, Buggy J, Elias L, Treon S, Matsui W, Richardson P, Munshi N, Anderson K Blood, 2012;120(9):1877-87. Species: Human Sample Type: recombinant IL-6 R in mouse serum
Inflammatory markers and the risk of hip fracture: the Women's Health Initiative. Authors: Barbour KE, Boudreau R, Danielson ME, Youk AO, Wactawski-Wende J, Greep NC, LaCroix AZ, Jackson RD, Wallace RB, Bauer DC, Allison MA, Cauley JA J. Bone Miner. Res., 2012;27(5):1167-76. Species: Human Sample Type: Serum
Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring. Authors: Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traore B, Doumbo S, Schollin J, Doumbo O, Montgomery SM, Sverremark-Ekstrom E Clin. Exp. Immunol., 2010;162(3):500-9. Species: Human Sample Type: Milk
Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease. Authors: Perez-Andres M, Almeida J, Martin-Ayuso M, De Las Heras N, Moro MJ, Martin-Nunez G, Galende J, Cuello R, Abuin I, Moreno I, Dominguez M, Hernandez J, Mateo G, San Miguel JF, Orfao A Int. J. Cancer, 2009;124(2):367-75. Species: Human Sample Type: Plasma
Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria. Authors: Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, Opelz G Transplantation, 2009;88(9):1109-16. Species: Human Sample Type: Urine
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Authors: Chauhan D, Singh AV, Brahmandam M, Carrasco R, Bandi M, Hideshima T, Bianchi G, Podar K, Tai YT, Mitsiades C, Raje N, Jaye DL, Kumar SK, Richardson P, Munshi N, Anderson KC Cancer Cell, 2009;16(4):309-23. Species: Human Sample Type: Serum
Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Authors: Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA Cancer Res., 2009;69(1):329-37. Species: Human Sample Type: Serum
Daily family assistance and inflammation among adolescents from Latin American and European backgrounds. Authors: Fuligni AJ, Telzer EH, Bower J, Irwin MR, Kiang L, Cole SW Brain Behav. Immun., 2009;23(6):803-9. Species: Human Sample Type: Plasma
Interleukin-6 and soluble interleukin-6 receptor levels as markers of disease extent and prognosis in neuroblastoma. Authors: Egler RA, Burlingame SM, Nuchtern JG, Russell HV Clin. Cancer Res., 2008;14(21):7028-34. Species: Human Sample Type: Plasma
Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Authors: Shariat SF, Karam JA, Walz J, Roehrborn CG, Montorsi F, Margulis V, Saad F, Slawin KM, Karakiewicz PI Clin. Cancer Res., 2008;14(12):3785-91. Species: Human Sample Type: Plasma
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Authors: Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J Blood, 2007;110(6):1748-55. Species: Human Sample Type: Cell Culture Supernates
Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. Authors: Cauley JA, Danielson ME, Boudreau RM, Forrest KY, Zmuda JM, Pahor M, Tylavsky FA, Cummings SR, Harris TB, Newman AB J. Bone Miner. Res., 2007;22(7):1088-95. Species: Human Sample Type: Serum
Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy. Authors: Sadeghi M, Susal C, Daniel V, Naujokat C, Zimmermann R, Huth-Kuhne A, Opelz G AIDS Res. Hum. Retroviruses, 2007;23(7):886-90. Species: Human Sample Type: Plasma
Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Authors: Richards PJ, Nowell MA, Horiuchi S, McLoughlin RM, Fielding CA, Grau S, Yamamoto N, Ehrmann M, Rose-John S, Williams AS, Topley N, Jones SA Arthritis Rheum., 2006;54(5):1662-72. Species: Human Sample Type: Serum
Effect of influenza vaccine on markers of inflammation and lipid profile. Authors: Tsai MY, Hanson NQ, Straka RJ, Hoke TR, Ordovas JM, Peacock JM, Arends VL, Arnett DK J. Lab. Clin. Med., 2005;145(6):323-7. Species: Human Sample Type: Plasma
Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection. Authors: Sadeghi M, Daniel V, Naujokat C, Wiesel M, Hergesell O, Opelz G Transpl. Int., 2005;18(2):177-85. Species: Human Sample Type: Plasma
Levels of soluble cytokine factors in temporomandibular joint effusions seen on magnetic resonance images. Authors: Kaneyama K, Segami N, Sun W, Sato J, Fujimura K Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005;99(4):411-8. Species: Human Sample Type: Synovial Fluid
Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failure. Authors: Hirota H, Izumi M, Hamaguchi T, Sugiyama S, Murakami E, Kunisada K, Fujio Y, Oshima Y, Nakaoka Y, Yamauchi-Takihara K Heart Vessels, 2004;19(5):237-41. Species: Human Sample Type: Plasma
Arenavirus-mediated liver pathology: acute lymphocytic choriomeningitis virus infection of rhesus macaques is characterized by high-level interleukin-6 expression and hepatocyte proliferation. Authors: Lukashevich IS, Tikhonov I, Rodas JD, Zapata JC, Yang Y, Djavani M, Salvato MS J. Virol., 2003;77(3):1727-37. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Serum
Effects of IL-6 variants in multiple myeloma: growth inhibition and induction of apoptosis in primary cells. Authors: Petrucci MT, Ricciardi MR, Gregorj C, Ciapponi L, Savino R, Ciliberto G, Tafuri A Leuk. Lymphoma, 2002;43(12):2369-75. Species: Human Sample Type: Serum
Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response. Authors: Carstanjen D, Regenfus M, Muller C, Salama A Exp. Hematol., 2001;29(7):812-21. Species: Human Sample Type: Plasma
Ovariectomy does not induce osteopenia through interleukin-6 in rhesus monkeys (Macaca mulatta). Authors: Keller ET, Binkley NC, Stebler BA, Hall DM, Johnston GM, Zhang J, Ershler WB Bone, 2000;26(1):55-62. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Bone Marrow Fluid
Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimers disease. Authors: Hampel H, Teipel SJ, Padberg F, Haslinger A, Riemenschneider M, Schwarz MJ, Kotter HU, Scheloske M, Buch K, Stubner S, Dukoff R, Lasser R, Moller N, Sunderland T, Rapoport SI, Moller HJ Brain Res., 1999;823(1):104-12. Species: Human Sample Type: CSF
Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130. Authors: Stubner S, Schon T, Padberg F, Teipel SJ, Schwarz MJ, Haslinger A, Buch K, Dukoff R, Lasser R, Moller N, Sunderland T, Rapoport SI, Moller HJ, Hampel H Neurosci. Lett., 1999;259(3):145-8. Species: Human Sample Type: CSF
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