| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Preclinical development of a humanized neutralizing antibody targeting HGF
Authors: H Kim, SH Hong, JY Kim, IC Kim, YW Park, SJ Lee, SW Song, JJ Kim, G Park, TM Kim, YH Kim, JB Park, J Chung, IH Kim
Exp. Mol. Med, 2017;49(3):e309.
Species: Human
Sample Type: Serum
Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes
PLoS ONE, 2016;11(12):e0168058.
Species: Human
Sample Type: Cell Culture Supernates
Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved
Authors: D Dauwe, B Pelacho, A Wibowo, AS Walravens, K Verdonck, H Gillijns, E Caluwe, P Pokreisz, N van Gastel, G Carmeliet, M Depypere, F Maes, N Vanden Dri, W Droogne, J Van Cleemp, J Vanhaecke, F Prosper, C Verfaillie, A Luttun, S Janssens
J Am Heart Assoc, 2016;5(4):.
Species: Human
Sample Type: Cell Culture Supernates
Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia
Stem Cell Res Ther, 2016;7(1):128.
Species: Human
Sample Type: Cell Culture Supernates
M-CSF in a new biomarker panel with HE4 and CA 125 in the diagnostics of epithelial ovarian cancer patients.
Authors: Bedkowska G, Lawicki S, Gacuta E, Pawlowski P, Szmitkowski M
J Ovarian Res, 2015;8(0):27.
Species: Human
Sample Type: Plasma
Multiple regulatory mechanisms of hepatocyte growth factor expression in malignant cells with a short poly(dA) sequence in the HGF gene promoter.
Authors: Sakai K, Takeda M, Okamoto I, Nakagawa K, Nishio K
Oncol Lett, 2015;9(1):405-410.
Species: Human
Sample Type: Cell Culture Supernates
The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.
Authors: Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor A, Yasuda Y, Niki T
BMC Cancer, 2015;15(0):82.
Species: Human
Sample Type: cell culture supernate
A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.
Authors: Tabernero J, Elez M, Herranz M, Rico I, Prudkin L, Andreu J, Mateos J, Carreras M, Han M, Gifford J, Credi M, Yin W, Agarwal S, Komarnitsky P, Baselga J
Clin Cancer Res, 2014;20(10):2793-804.
Species: Human
Sample Type: Serum
Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2014;110(1):26-33.
Species: Human
Sample Type: Plasma
Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells.
Authors: Berardis S, Lombard C, Evraerts J, El Taghdouini A, Rosseels V, Sancho-Bru P, Lozano J, van Grunsven L, Sokal E, Najimi M
PLoS ONE, 2014;9(1):e86137.
Species: Human
Sample Type: Cell Culture Supernates
Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma.
Authors: Imura, Yoshinor, Yasui, Hirohiko, Outani, Hidetats, Wakamatsu, Toru, Hamada, Kenichir, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Mol Cancer, 2014;13(0):185.
Species: Human
Sample Type: cell culture supernate
Diversity of biological effects induced by longwave UVA rays (UVA1) in reconstructed skin.
Authors: Marionnet C, Pierrard C, Golebiewski C, Bernerd F
PLoS ONE, 2014;9(8):e105263.
Species: Human
Sample Type: Cultured Media
Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate.
Authors: Chou M, Burnouf T, Wang T
PLoS ONE, 2014;9(6):e99145.
Species: Human
Sample Type: Cell Culture Supernates
Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cells.
Authors: Kinzebach S, Dietz L, Kluter H, Thierse H, Bieback K
BMC Cell Biol, 2013;14(0):48.
Species: Human
Sample Type: Cell Culture Supernates
The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro.
Authors: Li Q, Zhang A, Tao C, Li X, Jin P
Biochem Biophys Res Commun, 2013;441(3):675-80.
Species: Human
Sample Type: Cell Culture Supernates
Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases.
Authors: Wertenbroek, Marieke, Schepers, Marianne, Kamminga-Rasker, Hannetta, Bottema, Jan T, Muller Kobold, Anneke C, Roelofsen, Han, de Jong, Koert P
BMC Cancer, 2013;13(1):266.
Species: Human
Sample Type: Serum
Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
Authors: Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini M, Rosti V, Lo-Coco F, Locatelli F, Bernardo M
PLoS ONE, 2013;8(11):e76989.
Species: Human
Sample Type: cell culture supernate
Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma.
Authors: Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J, Pallota MG, Zarba JJ, Boyer M, Riordan S, Strickland A, Tebbutt N, Thomson B, Borbath I, De Greve J, Van Laethem J-, Van Steenbergen W, Van Vlierberghe H, Barrios C, Cosme de Oliveira A, Kotzev I, Takov D, Tchernev K, Burak K, Ma M, Metrakos P, Olweny C, Sherman M, Gamargo Garate C, Martinez-Castillo J, Beaugrand M, Bennouna J, Blanc J-, Bronowicki J-, Degos F, Dominguez S, Grange J-, Hillon P, Raoul J-, Seitz J-, Blum H, Buggisch P, Caspary W, Dollinger M, Gerken G, Goke B, Gregor M, Greten T, Haussinger D, Hilgard P, Scherübl J, Scheulen M, Schmid R, Spengler U, Wiest R, Zeuzem S, Arvanitakis C, Germanidis G, Katsos I, Figer A, Stemmer S, Amadori D, Bolondi L, Cognetti F, Craxi A, Farinati F, Gridelli C, Martoni A, Mazzaferro V, Porta C, Ricci S, Sangiovanni A, Santoro A, Trevisani F, Cisnero Garza LE, Gane E, ODonnell A, Leon J, Lozano A, Jassem J, Rydzewska G, Szawlowski A, Tomczak P, Badulescu F, Miron L, Kubyshkin V, Bruix J, Forner A, Bustamante Schneider J, Diago M, Montero Alvarez JL, Pascual S, RuÃÂz del Arbol L, Sangro B, Solá R, Tabernero J, Muellhaupt B, Roth A, Jeffry Evans TR, Falk S, Meyer T, Reeves H, Ross P, Befeler A, Boyer T, Britten C, Byrne T, Garcia-Tsao G, Gold P, Goldenberg A, Heuman D, Kennedy P, Koch A, Llovet JM, Marrero J, Schilsky M, Schwartz J, Schwartz M
Clin. Cancer Res., 2012;18(8):2290-300.
Species: Human
Sample Type: Plasma
Comparison of the levels of the growth factors in umbilical cord serum and human milk and its clinical significance.
Authors: Patki S, Patki U, Patil R, Indumathi S, Kaingade P, Bulbule A, Nikam A, Pishte A
Cytokine, 2012;59(2):305-8.
Species: Human
Sample Type: umbilical cord serum
Validation and quality control of ELISAs for the use with human saliva samples.
Authors: Jaedicke KM, Taylor JJ, Preshaw PM
J. Immunol. Methods, 2012;377(1):62-5.
Species: Human
Sample Type: Saliva
The secretion pattern of perivascular fat cells is different from that of subcutaneous and visceral fat cells.
Authors: Rittig K, Dolderer JH, Balletshofer B, Machann J, Schick F, Meile T, Kuper M, Stock UA, Staiger H, Machicao F, Schaller HE, Konigsrainer A, Haring HU, Siegel-Axel DI
Diabetologia, 2012;55(5):1514-25.
Species: Human
Sample Type: Serum
Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor beta and Notch signaling.
Authors: Robinson AP, Foraker JE, Ylostalo J, Prockop DJ
Stem Cells Dev., 2011;20(2):289-300.
Species: Human
Sample Type: Cell Culture Supernates
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.
Authors: Rauch C, Feifel E, Amann EM, Spotl HP, Schennach H, Pfaller W, Gstraunthaler G
ALTEX, 2011;28(4):305-16.
Species: Human
Sample Type: Cell Lysates
Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities.
Authors: Farha S, Asosingh K, Xu W, Sharp J, George D, Comhair S, Park M, Tang WH, Loyd JE, Theil K, Tubbs R, Hsi E, Lichtin A, Erzurum SC
Blood, 2011;117(13):3485-93.
Species: Human
Sample Type: Plasma
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2011;89(1):157-65.
Species: Human
Sample Type: Cell Culture Supernates
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
Authors: Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP
Nat. Cell Biol., 2010;12(5):468-76.
Species: Human
Sample Type: Cell Culture Supernates
Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumors.
Authors: Gordon MS, Sweeney CS, Mendelson DS
Clin. Cancer Res., 2010;16(2):699-710.
Species: Human
Sample Type: Plasma
Impact of serum hepatocyte growth factor on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small cell lung adenocarcinoma.
Authors: Kasahara K, Arao T, Sakai K, Matsumoto K, Sakai A, Kimura H, Sone T, Horiike A, Nishio M, Ohira T, Ikeda N, Yamanaka T, Saijo N, Nishio K
Clin. Cancer Res., 2010;16(18):4616-24.
Species: Human
Sample Type: Serum
Alternative proteolytic processing of hepatocyte growth factor during wound repair.
Authors: Buchstein N, Hoffmann D, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA
Am. J. Pathol., 2009;174(6):2116-28.
Species: Human
Sample Type: wound exudate
Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells.
Authors: Zdzisinska B, Bojarska-Junak A, Dmoszynska A, Kandefer-Szerszen M
Arch. Immunol. Ther. Exp. (Warsz.), 2008;56(3):207-21.
Species: Human
Sample Type: Cell Culture Supernates
Clinical correlations and prognostic relevance of HGF, VEGF AND FGF expression in Brazilian patients with non-Hodgkin lymphoma.
Authors: Etto L, Lacerda E, Baiocchi O, Silva V, Dalboni M, Alves A, Silva M, Vettore A, Colleoni G
Leuk. Lymphoma, 2008;49(2):257-64.
Species: Human
Sample Type: Serum
IFATS Series: FGF-2-induced HGF Secretion By Adipose-Derived Stromal Cells Inhibits Post-Injury Fibrogenesis Through A JNK-Dependent Mechanism.
Authors: Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K
Stem Cells, 2008;0(0):.
Species: Human
Sample Type: Conditioned media
Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis.
Authors: Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM
Arthritis Rheum., 2007;56(7):2432-42.
Species: Human
Sample Type: Cell Culture Supernates
Hepatocyte growth factor levels in gingival crevicular fluid in health, disease, and after treatment.
Authors: Nagaraja C, Pradeep AR
J. Periodontol., 2007;78(4):742-7.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
A fusion protein of hepatocyte growth factor for immobilization to collagen.
Authors: Kitajima T, Terai H, Ito Y
Biomaterials, 2007;28(11):1989-97.
Species: Human
Sample Type: recombinant HGF
Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
Stem Cells, 2007;25(8):1862-71.
Species: Human
Sample Type: Cell Culture Supernates
Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells.
Authors: Lederle W, Stark HJ, Skobe M, Fusenig NE, Mueller MM
Am. J. Pathol., 2006;169(5):1767-83.
Species: Human
Sample Type: Cell Culture Supernates
Humoral and cellular factors responsible for coronary collateral formation.
Authors: Sherman JA, Hall A, Malenka DJ, De Muinck ED, Simons M
Am. J. Cardiol., 2006;98(9):1194-7.
Species: Human
Sample Type: Plasma
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005;175(9):6177-89.
Species: Human
Sample Type: Cell Culture Supernates
Relation of various plasma growth factor levels in patients with stable angina pectoris and total occlusion of a coronary artery to the degree of coronary collaterals.
Authors: Briguori C, Testa U, Colombo A, Petrucci E, Condorelli G, Airoldi F, Peschle C, Condorelli G
Am. J. Cardiol., 2005;97(4):472-6.
Species: Human
Sample Type: Serum
Hepatocyte growth factor in the vitreous fluid of patients with proliferative diabetic retinopathy: its relationship with vascular endothelial growth factor and retinopathy activity.
Authors: Simo R, Lecube A, Garcia-Arumi J, Carrasco E, Hernandez C
Diabetes Care, 2004;27(1):287-8.
Species: Human
Sample Type: Vitreous Humor
Differential macrophage infiltration in early and advanced endometriosis and adjacent peritoneum.
Authors: Khan KN, Masuzaki H, Fujishita A, Kitajima M, Sekine I, Ishimaru T
Fertil. Steril., 2004;81(3):652-61.
Species: Human
Sample Type: Cell Culture Supernates
Hepatocyte growth factor and its role in the pathogenesis of retinal detachment.
Authors: Jin M, Chen Y, He S, Ryan SJ, Hinton DR
Invest. Ophthalmol. Vis. Sci., 2004;45(1):323-9.
Species: Rabbit
Sample Type: Vitreous Humor
Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells.
Authors: Rehman J, Li J, Parvathaneni L, Karlsson G, Panchal VR, Temm CJ, Mahenthiran J, March KL
J. Am. Coll. Cardiol., 2004;43(12):2314-8.
Species: Human
Sample Type: Plasma
Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome.
Authors: Matsushima A, Ogura H, Koh T, Fujita K, Yoshiya K, Sumi Y, Hosotsubo H, Kuwagata Y, Tanaka H, Shimazu T, Sugimoto H
J Trauma, 2004;56(2):259-64.
Species: Human
Sample Type: Plasma
Exhaled breath condensate and serum levels of hepatocyte growth factor in pneumonia.
Authors: Nayeri F, Millinger E, Nilsson I, Zetterström, Brudin L, Forsberg P
Respir Med, 2002;96(2):115-9.
Species: Human
Sample Type: Exhaled Breath Condensate (EBC)
Association of interleukin-6 and estradiol with hepatocyte growth factor in peritoneal fluid of women with endometriosis.
Authors: Khan KN, Masuzaki H, Fujishita A, Hamasaki T, Kitajima M, Hasuo A, Miyamura Y, Ishimaru T
Acta Obstet Gynecol Scand, 2002;81(8):764-71.
Species: Human
Sample Type: Peritoneal Fluid
Hepatocyte growth factor (HGF) system in gingiva: HGF activator expression by gingival epithelial cells.
Authors: Ohshima M, Sakai A, Sawamoto Y, Seki K, Ito K, Otsuka K
J Oral Sci, 2002;44(3):129-34.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
Selective plasma filtration for treatment of fulminant hepatic failure induced by D-galactosamine in a pig model.
Authors: Ho DW, Fan ST, To J, Woo YH, Zhang Z, Lau C, Wong J
Gut, 2002;50(6):869-76.
Species: Porcine
Sample Type: Plasma
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