| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved
Authors: D Dauwe, B Pelacho, A Wibowo, AS Walravens, K Verdonck, H Gillijns, E Caluwe, P Pokreisz, N van Gastel, G Carmeliet, M Depypere, F Maes, N Vanden Dri, W Droogne, J Van Cleemp, J Vanhaecke, F Prosper, C Verfaillie, A Luttun, S Janssens
J Am Heart Assoc, 2016;5(4):.
Species: Human
Sample Type: Cell Culture Supernates
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study
PLoS ONE, 2016;11(5):e0155242.
Species: Human
Sample Type: Serum
Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Sci Rep, 2016;6(0):29029.
Species: Human
Sample Type: Cell Culture Supernates
Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes
PLoS ONE, 2016;11(12):e0168058.
Species: Human
Sample Type: Cell Culture Supernates
A promising scaffold with excellent cytocompatibility and pro-angiogenesis action for dental tissue engineering: Strontium-doped calcium polyphosphate
Authors: H Qin, Z Yang, L Li, X Yang, J Liu, X Chen, X Yu
Dent Mater J, 2016;35(2):241-9.
Species: Human
Sample Type: Cell Culture Supernates
Breeding Strategy Determines Rupture Incidence in Post-Infarct Healing WARPing Cardiovascular Research.
Authors: Deckx S, Carai P, Bateman J, Heymans S, Papageorgiou A
PLoS ONE, 2015;10(9):e0139199.
Species: Rat
Sample Type: Cell Culture Supernates
Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis.
Authors: Candini O, Spano C, Murgia A, Grisendi G, Veronesi E, Piccinno M, Ferracin M, Negrini M, Giacobbi F, Bambi F, Horwitz E, Conte P, Paolucci P, Dominici M
Stem Cells, 2015;33(3):939-50.
Species: Human
Sample Type: Cell Culture Supernates
In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis.
Authors: Choi, Jane Ru, Pingguan-Murphy, Belinda, Wan Abas, Wan Abu, Yong, Kar Wey, Poon, Chi Tat, Noor Azmi, Mat Aden, Omar, Siti Zaw, Chua, Kien Hui, Xu, Feng, Wan Safwani, Wan Kama
PLoS ONE, 2015;10(1):e0115034.
Species: Human
Sample Type: Cell Culture Supernates
A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis.
Authors: Armacki, M, Joodi, G, Nimmagadda, S C, de Kimpe, L, Pusapati, G V, Vandoninck, S, Van Lint, J, Illing, A, Seufferlein, T
Oncogene, 2014;33(9):1167-80.
Species: Human
Sample Type: Cell Culture Supernates
Malondialdehyde mediates oxidized LDL-induced coronary toxicity through the Akt-FGF2 pathway via DNA methylation.
Authors: Yang T, Chen Y, Chang S, Chen C, Chang P, Lu S
J Biomed Sci, 2014;21(0):11.
Species: Human
Sample Type: Cell Culture Supernates
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
Authors: Ricard N, Tu L, Le Hiress M, Huertas A, Phan C, Thuillet R, Sattler C, Fadel E, Seferian A, Montani D, Dorfmuller P, Humbert M, Guignabert C
Circulation, 2014;129(15):1586-97.
Species: Human
Sample Type: Cell Culture Supernates
A novel decoy receptor fusion protein for FGF-2 potently inhibits tumour growth.
Authors: Li D, Wei X, Xie K, Chen K, Li J, Fang J
Br J Cancer, 2014;111(1):68-77.
Species: Human
Sample Type: recombinant protein
Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate.
Authors: Chou M, Burnouf T, Wang T
PLoS ONE, 2014;9(6):e99145.
Species: Human
Sample Type: Cell Culture Supernates
Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.
Authors: Ho I, Toh H, Ng W, Teo Y, Guo C, Hui K, Lam P
Stem Cells, 2013;31(1):146-55.
Species: Human
Sample Type: Tissue Lysate
The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro.
Authors: Li Q, Zhang A, Tao C, Li X, Jin P
Biochem Biophys Res Commun, 2013;441(3):675-80.
Species: Human
Sample Type: Cell Culture Supernates
Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cells.
Authors: Kinzebach S, Dietz L, Kluter H, Thierse H, Bieback K
BMC Cell Biol, 2013;14(0):48.
Species: Human
Sample Type: Cell Culture Supernates
Biomarkers for antitumor activity of bevacizumab in gastric cancer models.
Authors: Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K
BMC Cancer, 2012;12(0):37.
Species: Human
Sample Type: Tissue Homogenates
Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy.
Authors: Qin W, Zhang K, Kliethermes B, Ruhlen RL, Browne EP, Arcaro KF, Sauter ER
BMC Cancer, 2012;12(0):100.
Species: Human
Sample Type: Milk
Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model.
Authors: Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L
Am J Pathol, 2012;181(5):1540-59.
Species: Human
Sample Type: Cell Culture Supernates
Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells.
Authors: Marshall ME, Hinz TK, Kono SA, Singleton KR, Bichon B, Ware KE, Marek L, Frederick BA, Raben D, Heasley LE
Clin. Cancer Res., 2011;17(15):5016-25.
Species: Human
Sample Type: Cell Lysates
In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer.
Authors: Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, Thill M, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2609-15.
Species: Human
Sample Type: Serum
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.
Authors: Rauch C, Feifel E, Amann EM, Spotl HP, Schennach H, Pfaller W, Gstraunthaler G
ALTEX, 2011;28(4):305-16.
Species: Human
Sample Type: Cell Lysates
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2011;89(1):157-65.
Species: Human
Sample Type: Cell Culture Supernates
Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model.
Authors: Brave SR, Eberlein C, Shibuya M, Wedge SR, Barry ST
Angiogenesis, 2010;13(4):337-47.
Species: Human
Sample Type: Cell Culture Supernates
Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.
Authors: Ding W, Knox TR, Tschumper RC
Blood, 2010;116(16):2984-93.
Species: Human
Sample Type: Platelet-Poor Plasma
Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis.
Authors: Quintas-Cardama A, Kantarjian HM, Manshouri T, Thomas D, Cortes J, Ravandi F, Garcia-Manero G, Ferrajoli A, Bueso-Ramos C, Verstovsek S
J. Clin. Oncol., 2009;27(28):4760-6.
Species: Human
Sample Type: Plasma
A urinary biomarker profile for children with HIV-associated renal diseases.
Authors: Soler-Garcia AA, Rakhmanina NY, Mattison PC, Ray PE
Kidney Int., 2009;76(2):207-14.
Species: Human
Sample Type: Urine
Tumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2.
Authors: Farrow B, Berger DH, Rowley D
J. Surg. Res., 2009;156(1):155-60.
Species: Human
Sample Type: Cell Culture Supernates
Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
Authors: Wang C, Duan H, He L
Eur. J. Pharmacol., 2009;612(1):143-52.
Species: Mouse
Sample Type: Air Pouch Exudate
Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivo.
Authors: Nakano Y, Oyamada M, Dai P, Nakagami T, Kinoshita S, Takamatsu T
Invest. Ophthalmol. Vis. Sci., 2008;49(1):93-104.
Species: Rat
Sample Type: Aqueous humor
Observations on the microvasculature of bone defects filled with biodegradable nanoparticulate hydroxyapatite.
Authors: Kilian O, Wenisch S, Karnati S, Baumgart-Vogt E, Hild A, Fuhrmann R, Jonuleit T, Dingeldein E, Schnettler R, Franke RP
Biomaterials, 2008;29(24):3429-37.
Species: Porcine
Sample Type: Plasma
Elevated fibroblast growth factor-2 increases tumor necrosis factor-alpha induced endothelial cell death in high glucose.
Authors: Clyne AM, Zhu H, Edelman ER
J. Cell. Physiol., 2008;217(1):86-92.
Species: Porcine
Sample Type: Whole Cells
Clinical correlations and prognostic relevance of HGF, VEGF AND FGF expression in Brazilian patients with non-Hodgkin lymphoma.
Authors: Etto L, Lacerda E, Baiocchi O, Silva V, Dalboni M, Alves A, Silva M, Vettore A, Colleoni G
Leuk. Lymphoma, 2008;49(2):257-64.
Species: Human
Sample Type: Serum
Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation.
Authors: Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH
Diabetes, 2007;57(1):158-66.
Species: Bovine
Sample Type: Cell Culture Supernates
Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction.
Authors: Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D
Clin. Sci., 2007;112(1):51-7.
Species: Human
Sample Type: Serum
Sca-1(+) Hematopoietic Cell-based Gene Therapy with a Modified FGF-2 Increased Endosteal/Trabecular Bone Formation in Mice.
Authors: Hall SL, Lau KH, Chen ST, Wergedal JE, Srivastava A, Klamut H, Sheng MH, Gridley DS, Mohan S, Baylink DJ
Mol. Ther., 2007;15(10):1881-9.
Species: Mouse
Sample Type: Serum
Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma.
Authors: Yashiro M, Nakazawa K, Tendo M, Kosaka K, Shinto O, Hirakawa K
Int. J. Cancer, 2007;120(3):686-93.
Species: Human
Sample Type: Cell Culture Supernates
Fibroblast growth factor-2 expression is altered in lambs with increased pulmonary blood flow and pulmonary hypertension.
Authors: Wedgwood S, Devol JM, Grobe A, Benavidez E, Azakie A, Fineman JR, Black SM
Pediatr. Res., 2007;61(1):32-6.
Species: Ovine
Sample Type: Cell Culture Supernates
Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation.
Authors: Herrmann S, Green J, Weber T, Scharfenberger A
Bone, 2006;39(5):1156-63.
Species: Human
Sample Type: Tissue Homogenates
Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
Glia, 2006;53(8):845-57.
Species: Human
Sample Type: Cell Culture Supernates
Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
J. Immunol., 2006;177(5):3388-97.
Species: Mouse
Sample Type: Tissue Homogenates
A phase I biological and pharmacologic study of the heparanase inhibitor PI-88 in patients with advanced solid tumors.
Authors: Basche M, Gustafson DL, Holden SN, OBryant CL, Gore L, Witta S, Schultz MK, Morrow M, Levin A, Creese BR, Kangas M, Roberts K, Nguyen T, Davis K, Addison RS, Moore JC, Eckhardt SG
Clin. Cancer Res., 2006;12(18):5471-80.
Species: Human
Sample Type: Urine
Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease.
Authors: Molica S, Vitelli G, Mirabelli R, Digiesu G, Giannarelli D, Cuneo A, Ribatti D, Vacca A
Leuk. Lymphoma, 2006;47(6):1034-40.
Species: Human
Sample Type: Serum
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005;175(9):6177-89.
Species: Human
Sample Type: Cell Culture Supernates
Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector.
Authors: Hiraide A, Yokoo N, Xin KQ, Okuda K, Mizukami H, Ozawa K, Saito T
Hum. Gene Ther., 2005;16(12):1413-21.
Species: Rat
Sample Type: Cell Culture Supernates
Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension.
Authors: Rodriguez-Porcel M, Zhu XY, Chade AR, Amores-Arriaga B, Caplice NM, Ritman EL, Lerman A, Lerman LO
Am. J. Physiol. Heart Circ. Physiol., 2005;290(3):H978-84.
Species: Porcine
Sample Type: Tissue Homogenates
Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.
Authors: Stapelberg M, Gellert N, Swettenham E, Tomasetti M, Witting PK, Procopio A, Neuzil J
J. Biol. Chem., 2005;280(27):25369-76.
Species: Human
Sample Type: Cell Culture Supernates
Relation of various plasma growth factor levels in patients with stable angina pectoris and total occlusion of a coronary artery to the degree of coronary collaterals.
Authors: Briguori C, Testa U, Colombo A, Petrucci E, Condorelli G, Airoldi F, Peschle C, Condorelli G
Am. J. Cardiol., 2005;97(4):472-6.
Species: Human
Sample Type: Serum
Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
Authors: Iversen PO, Wiig H
Clin. Cancer Res., 2005;11(19):6793-9.
Species: Human
Sample Type: Plasma
Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury.
Authors: Mahmood A, Lu D, Chopp M
J. Neurotrauma, 2004;21(1):33-9.
Species: Rat
Sample Type: Tissue Homogenates
A potential pro-angiogenic cell therapy with human placenta-derived mesenchymal cells.
Authors: Nishishita T, Ouchi K, Zhang X, Inoue M, Inazawa T, Yoshiura K, Kuwabara K, Nakaoka T, Watanabe N, Igura K, Takahashi TA, Yamashita N
Biochem. Biophys. Res. Commun., 2004;325(1):24-31.
Species: Human
Sample Type: Cell Lysates
Transplantation of transduced retinal pigment epithelium in rats.
Authors: Saigo Y, Abe T, Hojo M, Tomita H, Sugano E, Tamai M
Invest. Ophthalmol. Vis. Sci., 2004;45(6):1996-2004.
Species: Rat
Sample Type: Cell Culture Supernates
beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.
Authors: Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ
Cancer Res., 2003;63(12):3145-53.
Species: Mouse
Sample Type: Serum
Have urinary levels of the angiogenic factors, basic fibroblast growth factor and vascular endothelial growth factor, a prognostic value in childhood acute lymphoblastic leukaemia?
Authors: Schneider P, Vasse M, Legrand E, Callat MP, Vannier JP
Br. J. Haematol., 2003;122(1):163-4.
Species: Human
Sample Type: Urine
Low-density lipoprotein in hypercholesterolemic human plasma induces vascular endothelial cell apoptosis by inhibiting fibroblast growth factor 2 transcription.
Authors: Chen CH, Jiang T, Yang JH, Jiang W, Lu J, Marathe GK, Pownall HJ, Ballantyne CM, McIntyre TM, Henry PD, Yang CY
Circulation, 2003;107(16):2102-8.
Species: Bovine
Sample Type: Cell Lysates
Diabetes can alter the signal transduction pathways in the lens of rats.
Authors: Zatechka DS, Kador PF, Garcia-Castineiras S, Lou MF
Diabetes, 2003;52(4):1014-22.
Species: Rat
Sample Type: Vitreous Humor
Retinoscleral control of scleral remodelling in refractive development: a role for endogenous FGF-2?
Authors: Gentle A, McBrien NA
Cytokine, 2002;18(6):344-8.
Species: Avian - Tree Shrew
Sample Type: Tissue Homogenates
Sugar-induced modification of fibroblast growth factor 2 reduces its angiogenic activity in vivo.
Authors: Facchiano F, Lentini A, Fogliano V, Mancarella S, Rossi C, Facchiano A, Capogrossi MC
Am. J. Pathol., 2002;161(2):531-41.
Species: Bovine
Sample Type: Cell Culture Supernates
Basic fibroblast growth factor in human saliva decreases with aging.
Authors: Westermark A, Pyykko I, Magnusson M, Ishizaki H, Jantti P, van Setten G
Laryngoscope, 2002;112(5):887-9.
Species: Human
Sample Type: Saliva
High basic fibroblast growth factor levels in nipple aspirate fluid are correlated with breast cancer.
Authors: Hsiung R, Zhu W, Klein G, Qin W, Rosenberg A, Park P, Rosato E, Sauter E
Cancer J, 2002;8(4):303-10.
Species: Human
Sample Type: Nipple aspirate fluid
Circadian variations of transforming growth factor-beta2 and basic fibroblast growth factor in the rabbit aqueous humor.
Authors: Liu JH
Curr. Eye Res., 2002;24(1):75-80.
Species: Rabbit
Sample Type: Aqueous humor
Increase in gap junctional intercellular communication by high molecular weight hyaluronic acid associated with fibroblast growth factor 2 and keratinocyte growth factor production in normal human dermal fibroblasts.
Authors: Park JU, Tsuchiya T
Tissue Eng., 2002;8(3):419-27.
Species: Human
Sample Type: Cell Culture Supernates
AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.
Authors: Truckenmiller ME, Vawter MP, Zhang P, Conejero-Goldberg C, Dillon-Carter O, Morales N, Cheadle C, Becker KG, Freed WJ
Exp. Neurol., 2002;175(0):318.
Species: Rat
Sample Type: Cell Culture Supernates
Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts.
Authors: Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U
Eur. J. Appl. Physiol., 2001;86(1):48-52.
Species: Human
Sample Type: Cell Culture Supernates
Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts in vivo.
Authors: Westphal JR, Vant Hullenaar R, Peek R, Willems RW, Crickard K, Crickard U, Askaa J, Clemmensen I, Ruiter DJ, De Waal RM
Int. J. Cancer, 2000;86(6):768-76.
Species: Human
Sample Type: Cell Culture Supernates
Intestinal mucosal secretion of basic fibroblast growth factor in patients with ulcerative colitis.
Authors: Thorn M, Raab Y, Larsson A, Gerdin B, Hallgren R
Scand. J. Gastroenterol., 2000;35(4):408-12.
Species: Human
Sample Type: perfusion fluid
Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome.
Authors: Soubrier M, Sauron C, Souweine B, Larroche C, Wechsler B, Guillevin L, Piette JC, Rousset H, Deteix P
Am. J. Kidney Dis., 1999;34(4):633-8.
Species: Human
Sample Type: Serum
Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells.
Authors: Gu JW, Adair TH
Am. J. Physiol., 1997;273(2):H628-33.
Species: Canine
Sample Type: Cell Culture Supernates
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