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Human Cytochrome c Quantikine SixPak (6 Plates) (1 PK)

货号: SCTC0 基本售价: 31934.7 元 规格: 1 PACK

产品信息

概述
货号SCTC0
描述The Quantikine Human Cytochrome c Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human cytochrome c in cell lysates.
别名CYCHCS; CYCS; Cytochrome c; cytochrome c, somatic; THC4;
反应种属Human
目标/特异性Natural human Cytochrome c
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
54205 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Oxidative stress-mediated apoptosis induced by ethanolic mango seed extract in cultured estrogen receptor positive breast cancer MCF-7 cells.
Authors: Abdullah A, Mohammed A, Rasedee A, Mirghani M
Int J Mol Sci, 2015;16(2):3528-36.
Species: Human
Sample Type: Cell Lysates

Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris.
Authors: Chen Y, Chernyavsky A, Webber R, Grando S, Wang P
J Biol Chem, 2015;290(39):23826-37.
Species: Human
Sample Type: Cell Culture Supernates

Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function.
Authors: Sjovall F, Morota S, Asander Frostner E, Hansson M, Elmer E
PLoS ONE, 2014;9(5):e97673.
Species: Human
Sample Type: Cell Lysates

Antimitochondrial autoantibodies in pemphigus vulgaris: a missing link in disease pathophysiology.
Authors: Marchenko S, Chernyavsky AI, Arredondo J, Gindi V, Grando SA
J. Biol. Chem., 2010;285(6):3695-704.
Species: Human
Sample Type: Cell Lysates

Roux-en-Y gastric bypass reverses renal glomerular but not tubular abnormalities in excessively obese diabetics.
Authors: Saliba J, Kasim NR, Tamboli RA, Isbell JM, Marks P, Feurer ID, Ikizler A, Abumrad NN
Surgery, 2010;147(2):282-7.
Species: Human
Sample Type: Urine

Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression.
Authors: Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, Takada K, Carlson NE, Carrasco DE, Tai YT, Raje N, Letai AG, Anderson KC, Carrasco DR
Blood, 2009;114(13):2699-708.
Species: Human
Sample Type: Cell Culture Supernates

Apolipoprotein-J prevention of fetal cardiac myoblast apoptosis induced by ethanol.
Authors: Li Y, Sagar MB, Wassler M, Shelat H, Geng YJ
Biochem. Biophys. Res. Commun., 2007;357(1):157-61.
Species: Canine
Sample Type: Cell Lysates

Glycyrrhizin protection against 3-morpholinosydnonime-induced mitochondrial dysfunction and cell death in lung epithelial cells.
Authors: Lee CS, Kim YJ, Han ES
Life Sci., 2007;80(19):1759-67.
Species: Human
Sample Type: Cell Lysates

Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.
Authors: Mookherjee P, Quintanilla R, Roh MS, Zmijewska AA, Jope RS, Johnson GV
J. Cell. Biochem., 2007;102(1):196-210.
Species: Human
Sample Type: Cell Culture Supernates

Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.
Authors: De Milito A, Iessi E, Logozzi M, Lozupone F, Spada M, Marino ML, Federici C, Perdicchio M, Matarrese P, Lugini L, Nilsson A, Fais S
Cancer Res., 2007;67(11):5408-17.
Species: Human
Sample Type: Cell Lysates

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
Authors: Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH
Nat. Cell Biol., 2006;8(12):1348-58.
Species: Human
Sample Type: Cell Culture Supernates

The apoptosis effect of hispolon from Phellinus linteus (Berkeley & Curtis) Teng on human epidermoid KB cells.
Authors: Chen W, He FY, Li YQ
J Ethnopharmacol, 2006;105(1):280-5.
Species: Human
Sample Type: Cell Lysates

Ebselen inhibits p38 mitogen-activated protein kinase-mediated endothelial cell death by hydrogen peroxide.
Authors: Ali N, Yoshizumi M, Tsuchiya K, Kyaw M, Fujita Y, Izawa Y, Abe S, Kanematsu Y, Kagami S, Tamaki T
Eur. J. Pharmacol., 2004;485(1):127-35.
Species: Human
Sample Type: Cell Lysates

Differential response of MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents.
Authors: Bang JH, Han ES, Lim I
Biochem. Pharmacol., 2004;68(4):659-66.
Species: Human
Sample Type: Cell Lysates

Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium.
Authors: Jow GM, Chou CJ, Chen BF, Tsai JH
Cancer Lett., 2004;216(2):165-73.
Species: Human
Sample Type: Cell Lysates

The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis.
Authors: Panduri V, Weitzman SA, Chandel N, Kamp DW
Am. J. Respir. Cell Mol. Biol., 2003;28(2):241-8.
Species: Human
Sample Type: Cell Lysates

Release of intact, monomeric cytochrome c from apoptotic and necrotic cells.
Authors: Jemmerson R, LaPlante B, Treeful A
Cell Death Differ., 2002;9(5):538-48.
Species: Human
Sample Type: Cell Culture Supernates

Bcl-2 phosphorylation and proteasome-dependent degradation induced by paclitaxel treatment: consequences on sensitivity of isolated mitochondria to Bid.
Authors: Brichese L, Barboule N, Heliez C, Valette A
Exp. Cell Res., 2002;278(1):101-11.
Species: Human
Sample Type: Cell Lysates

Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis.
Authors: Rajalingam K, Al-Younes H, Muller A, Meyer TF, Szczepek AJ, Rudel T
Infect. Immun., 2001;69(12):7880-8.
Species: Human
Sample Type: Cell Lysates

Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells.
Authors: Jiang C, Wang Z, Ganther H, Lu J
Cancer Res., 2001;61(7):3062-70.
Species: Human
Sample Type: Cell Lysates

Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2.
Authors: Poulaki V, Mitsiades N, Romero ME, Tsokos M
Cancer Res., 2001;61(12):4864-72.
Species: Human
Sample Type: Cell Lysates

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景Cytochrome c is a small, highly conserved, heme-containing protein involved in mitochondrial electron transport. Cytochrome c is released from the mitochondria in response to pro-apoptotic stimuli and serves as a cofactor in initiating the activation of the APAF-1/Caspase-9 complex. The effect of specific proteins and/or small molecules on the initiation of the intrinsic apoptotic pathway can be evaluated in an in vitro system of isolated mitochondria by monitoring the release of cytochrome c.
运输条件Blue Ice
存放说明4℃
参考文献
  • ALS Related Molecules
  • Bcl-2 Proteins and Regulators
  • Mitochondrial Proteins