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Human G-CSF Quantikine SixPak (6 Plates) (1 PK)

货号: SCS50 基本售价: 31934.7 元 规格: 1 PACK

产品信息

概述
货号SCS50
描述The Quantikine Human G-CSF Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure G-CSF in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human G-CSF and antibodies raised against the protein. It has been shown to accurately quantitate recombinant human G-CSF. Results obtained using natural human G-CSF showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human G-CSF.
别名C17orf33; chromosome 17 open reading frame 33; colony stimulating factor 3 (granulocyte); CSF3; CSF3OS; Filgrastim; GCSF; G-CSF; GCSFlenograstim; granulocyte colony-stimulating factor; Lenograstim; MGC45931; pluripoietin;
全称
Granulocyte Colony Stimulating Factor
反应种属Human
目标/特异性Natural and recombinant human G-CSF
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
1440 (Human); 12985 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Regulation of Circulating Hematopoietic Stem/Progenitor Cells in Preterm Infants with Septicemia
Stem Cells Dev, 2016;0(0):.
Species: Human
Sample Type: Plasma

Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
Respir Res, 2016;17(1):36.
Species: Human
Sample Type: Cell Culture Supernates

Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of ?-tubulin deactylase
Nucleic Acids Res, 2016;0(0):.
Species: Human
Sample Type: Cell Culture Supernates

LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1.
Authors: Chang S, Lin S, Yang H, Chou Y, Gao J, Lu S
PLoS ONE, 2015;10(6):e0129685.
Species: Human
Sample Type: Cell Culture Supernates

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer.
Authors: Kumar, J, Fraser, F W, Riley, C, Ahmed, N, McCulloch, D R, Ward, A C
Br J Cancer, 2014;110(1):133-45.
Species: Human
Sample Type: Cell Culture Supernates

Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
Cytokine, 2009;47(3):206-13.
Species: Human
Sample Type: Plasma

Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs.
Authors: Makam M, Diaz D, Laval J, Gernez Y, Conrad CK, Dunn CE, Davies ZA, Moss RB, Herzenberg LA, Herzenberg LA, Tirouvanziam R
Proc. Natl. Acad. Sci. U.S.A., 2009;106(14):5779-83.
Species: Human
Sample Type: Plasma

Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
Authors: Fox E, Widemann BC, Hawkins DS, Jayaprakash N, Dagher R, Aikin AA, Bernstein D, Long L, Mackall C, Helman L, Steinberg SM, Balis FM
Clin. Cancer Res., 2009;15(23):7361-7.
Species: Human
Sample Type: Serum

Novel immunocompetent murine tumor model for evaluation of conditionally replication-competent (oncolytic) murine adenoviral vectors.
Authors: Robinson M, Li B, Ge Y, Ko D, Yendluri S, Harding T, VanRoey M, Spindler KR, Jooss K
J. Virol., 2009;83(8):3450-62.
Species: Human
Sample Type: Cell Culture Supernates

Hematopoietic progenitor cell mobilization and harvesting in children with malignancies: do the advantages of pegfilgrastim really translate into clinical benefit?
Authors: Merlin E, Zohar S, Jérôme C, Veyrat-Masson R, Marceau G, Paillard C, Auvrignon A, Le Moine P, Gandemer V, Sapin V, Halle P, Boiret-Dupre N, Chevret S, Demeocq F, Dubray C, Kanold J
Bone Marrow Transplant., 2009;43(12):919-25.
Species: Human
Sample Type: Serum

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008;36(8):1035-46.
Species: Human
Sample Type: Cell Culture Supernates

Staphylococcus aureus in nasal lavage and biopsy of patients with chronic rhinosinusitis.
Authors: Niederfuhr A, Kirsche H, Deutschle T, Poppert S, Riechelmann H, Wellinghausen N
Allergy, 2008;63(10):1359-67.
Species: Human
Sample Type: nasal lavage

Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.
Authors: Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL
J. Immunol., 2008;180(5):3520-34.
Species: Human
Sample Type: Cell Culture Supernates

Does granulocyte colony-stimulating factor ameliorate the proinflammatory response in human meningococcal septic shock?
Authors: Rojahn A, Brusletto B, Ovstebo R, Haug KB, Kierulf P, Brandtzaeg P
Crit. Care Med., 2008;36(9):2583-9.
Species: Human
Sample Type: Plasma

Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
Int. J. Cancer, 2006;119(10):2313-21.
Species: Human
Sample Type: Cell Culture Supernates

Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA
Blood, 2005;105(2):830-7.
Species: Human
Sample Type: Cell Culture Supernates

Is granulocyte colony-stimulating factor level predictive for human IVF outcome?
Authors: Salmassi A, Schmutzler AG, Schaefer S, Koch K, Hedderich J, Jonat W, Mettler L
Hum. Reprod., 2005;20(9):2434-40.
Species: Human
Sample Type: Follicular Fluid

Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein.
Authors: Cox GN, Smith DJ, Carlson SJ, Bendele AM, Chlipala EA, Doherty DH
Exp. Hematol., 2004;32(5):441-9.
Species: Human
Sample Type: Plasma

Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis.
Authors: Lamming CE, Augustin L, Blackstad M, Lund TC, Hebbel RP, Verfaillie CM
J. Clin. Invest., 2003;111(6):811-9.
Species: Human
Sample Type: Serum

Retroviral interleukin 1alpha gene transfer in bone marrow stromal cells in a primate model: induction of myelopoiesis stimulation.
Authors: de Revel T, Becard N, Sorg T, Rousseau S, Spano JP, Thiebot H, Methali M, Gras G, Le Grand R, Dormont D
Br. J. Haematol., 2002;118(3):875-84.
Species: Primate- Macaca fascicularis (Cynomolgus/Crab-eating Monkey)
Sample Type: Cell Culture Supernates

Distinct hematopoietic support by two human stromal cell lines.
Authors: Loeuillet C, Bernard G, Remy-Martin J, Saas P, Herve P, Douay L, Chalmers D
Exp. Hematol., 2001;29(6):736-45.
Species: Human
Sample Type: Cell Culture Supernates

Glioblastoma causing granulocytosis by secretion of granulocyte-colony-stimulating factor.
Authors: Hintzen RQ, Voormolen J, Sonneveld P, van Duinen SG
Neurology, 2000;54(1):259-61.
Species: Human
Sample Type: CSF

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Authors: Fadok, V A, Bratton, D L, Konowal, A, Freed, P W, Westcott, J Y, Henson, P M
J Clin Invest, 1998;101(4):890-8.
Species: Human
Sample Type: Cell Culture Supernates

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景G-CSF (granulocyte-colony stimulating factor) is a secreted glycoprotein that regulates the proliferation, differentiation, and activation of neutrophilic granulocyte lineage cells. It also enhances M-CSF induced monocyte differentiation and the proliferation of Th2-inducing dendritic cells. G-CSF promotes the development of T cell immune tolerance as well as tissue recovery following myocardial infarction and cerebral ischemia. It signals through G-CSF R/CD114 on monocytes, neutrophils, megakaryocytes, platelets, myeloid progenitors, trophoblasts and placenta, endothelial cells, and various tumor cell types. Mutations in G-CSF R are associated with congenital neutropenia.
运输条件Blue Ice
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参考文献
  • ALS Related Molecules
  • Cytokines and Receptors in Angiogenesis
  • Gametes and Fertilization
  • IL-6 Family
  • Macrophage Activation Markers