| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.
Authors: Paoloni M, Mazcko C, Selting K, Lana S, Barber L, Phillips J, Skorupski K, Vail D, Wilson H, Biller B, Avery A, Kiupel M, LeBlanc A, Bernhardt A, Brunkhorst B, Tighe R, Khanna C
PLoS ONE, 2015;10(6):e0129954.
Species: Human
Sample Type: Serum
Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2014;110(1):26-33.
Species: Human
Sample Type: Plasma
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages.
Authors: Haselow K, Bode J, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp A, Haussinger D, Graf D
J Leukoc Biol, 2013;94(6):1253-64.
Species: Human
Sample Type: cell culture supernate
Efficacy of oncolytic adenovirus expressing suicide genes and interleukin-12 in preclinical model of prostate cancer.
Authors: Freytag, S O, Barton, K N, Zhang, Y
Gene Ther, 2013;20(12):1131-9.
Species: Human
Sample Type: cell culture supernate
Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
J Transl Med, 2011;9(0):151.
Species: Human
Sample Type: Cell Culture Supernates
HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
Leukemia, 2011;25(1):161-8.
Species: Human
Sample Type: Cell Culture Supernates
Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma.
Authors: Vyth-Dreese FA, Sein J, van de Kasteele W, Dellemijn TA, van den Bogaard C, Nooijen WJ, de Gast GC, Haanen JB, Bex A
Clin. Exp. Immunol., 2010;162(3):447-59.
Species: Human
Sample Type: Plasma
CD14-independent responses induced by a synthetic lipid A mimetic.
Authors: Legat A, Thomas S, Hermand P, Van Mechelen M, Goldman M, De Wit D
Eur J Immunol, 2010;40(3):797-802.
Species: Human
Sample Type: Cell Culture Supernates
Immunologic markers as predictors of tuberculosis-associated immune reconstitution inflammatory syndrome in HIV and tuberculosis coinfected persons in Thailand.
Authors: Tieu HV, Ananworanich J, Avihingsanon A, Apateerapong W, Sirivichayakul S, Siangphoe U, Klongugkara S, Boonchokchai B, Hammer SM, Manosuthi W
AIDS Res. Hum. Retroviruses, 2009;25(11):1083-9.
Species: Human
Sample Type: Serum
Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
Authors: Chase JC, Celli J, Bosio CM
Infect. Immun., 2009;77(1):180-95.
Species: Human
Sample Type: Cell Culture Supernates
Cerebrospinal fluid levels of interleukin-6 and interleukin-12 in children with meningitis.
Authors: Hsieh CC, Lu JH, Chen SJ, Lan CC, Chow WC, Tang RB
Cytotechnology, 2009;25(4):461-5.
Species: Human
Sample Type: CSF
Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
Eur. J. Immunol., 2008;38(4):1012-23.
Species: Human
Sample Type: Cell Culture Supernates
In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø
J. Interferon Cytokine Res., 2008;28(5):297-310.
Species: Human
Sample Type: Cell Culture Supernates
Chemokines CXCL10 and CXCL11 in the cerebrospinal fluid of patients with tick-borne encephalitis.
Authors: Lepej SZ, Misic-Majerus L, Jeren T, Rode OD, Remenar A, Sporec V, Vince A
Acta Neurol. Scand., 2007;115(2):109-14.
Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells.
Authors: Irhimeh MR, Fitton JH, Lowenthal RM
Exp. Hematol., 2007;35(6):989-94.
Species: Human
Sample Type: Plasma
Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
Authors: Little RF, Aleman K, Kumar P, Wyvill KM, Pluda JM, Read-Connole E, Wang V, Pittaluga S, Catanzaro AT, Steinberg SM, Yarchoan R
Blood, 2007;110(13):4165-71.
Species: Human
Sample Type: Serum
Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis.
Authors: Frances R, Gonzalez-Navajas JM, Zapater P, Munoz C, Cano R, Pascual S, Santana F, Marquez D, Perez-Mateo M, Such J
Clin. Exp. Immunol., 2007;150(2):230-7.
Species: Human
Sample Type: Serum
Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction.
Authors: Spensieri F, Fedele G, Fazio C, Nasso M, Stefanelli P, Mastrantonio P, Ausiello CM
Infect. Immun., 2006;74(5):2831-8.
Species: Human
Sample Type: Cell Culture Supernates
Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
Clin. Cancer Res., 2006;12(7):2055-60.
Species: Human
Sample Type: Plasma
C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease.
Authors: Makis AC, Hatzimichael EC, Stebbing J, Bourantas KL
Arch. Intern. Med., 2006;166(3):366-8.
Species: Human
Sample Type: Plasma
Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma.
Authors: Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M
J. Neuroimmunol., 2006;175(1):169-75.
Species: Human
Sample Type: Serum
Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis.
Authors: Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M
Am. J. Respir. Crit. Care Med., 2006;173(12):1370-6.
Species: Human
Sample Type: Serum
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production.
Authors: Vaknin-Dembinsky A, Balashov K, Weiner HL
J. Immunol., 2006;176(12):7768-74.
Species: Human
Sample Type: Cell Culture Supernates
Interleukin-12 and interleukin-16 in periodontal disease.
Authors: Tsai IS, Tsai CC, Ho YP, Ho KY, Wu YM, Hung CC
Cytokine, 2005;31(1):34-40.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission.
Authors: Hajnicka V, Vancova I, Kocakova P, Slovak M, Gasperik J, Slavikova M, Hails RS, Labuda M, Nuttall PA
Parasitology, 2005;130(0):333-42.
Species: Human
Sample Type: Saliva
Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.
Authors: Jensen J, Krakauer M, Sellebjerg F
Cytokine, 2005;29(1):24-30.
Species: Human
Sample Type: Plasma
Effect of piceatannol in human monocyte-derived dendritic cells in vitro.
Authors: Takei M, Umeyama A, Arihara S, Matsumoto H
J Pharm Sci, 2005;94(5):974-82.
Species: Human
Sample Type: Cell Culture Supernates
Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
J. Androl., 2004;25(2):250-4.
Species: Human
Sample Type: seminal plasma
Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients.
Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S
J. Allergy Clin. Immunol., 2004;114(3):538-44.
Species: Human
Sample Type: Cell Culture Supernates
Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria.
Authors: Chaiyaroj SC, Rutta AS, Muenthaisong K, Watkins P, Na Ubol M, Looareesuwan S
Acta Trop., 2004;89(3):319-27.
Species: Human
Sample Type: Plasma
NK cells regulate CD8+ T cell effector function in response to an intracellular pathogen.
Authors: Vankayalapati R, Klucar P, Wizel B, Weis SE, Samten B, Safi H, Shams H, Barnes PF
J. Immunol., 2004;172(1):130-7.
Species: Human
Sample Type: Cell Culture Supernates
Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18.
Authors: Garofalo RP, Hintz KH, Hill V, Ogra PL, Welliver RC
J. Med. Virol., 2004;73(2):289-94.
Species: Human
Sample Type: Nasopharyngeal Secretions
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
J. Virol., 2004;78(12):6151-61.
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Type: Cell Culture Supernates
Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: a pilot study.
Authors: Ciprandi G, Tosca MA, Milanese M, Caligo G, Ricca V
Pediatr Allergy Immunol, 2004;15(2):148-51.
Species: Human
Sample Type: nasal lavage
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
J. Immunol., 2004;173(7):4433-42.
Species: Human
Sample Type: Cell Culture Supernates
Cytokine profile in Behcet's disease patients. Relationship with disease activity.
Authors: Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K
Scand. J. Rheumatol., 2002;31(4):205-10.
Species: Human
Sample Type: Serum
Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer.
Authors: Pages F, Lebel-Binay S, Vieillefond A, Deneux L, Cambillau M, Soubrane O, Debre B, Tardy D, Lemonne JL, Abastado JP, Fridman WH, Thiounn N
Clin. Exp. Immunol., 2002;127(2):303-9.
Species: Human
Sample Type: Urine
Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
Int. J. Cancer, 2002;101(2):183-9.
Species: Human
Sample Type: Ascites
HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Authors: Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
J. Immunol., 2002;169(11):6361-8.
Species: Human
Sample Type: Cell Culture Supernates
Interleukin-11 induces Th2 polarization of human CD4(+) T cells.
Authors: Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, Siena M, Grande A, Fogli M, Tura S, Lemoli RM
Blood, 2001;97(9):2758-63.
Species: Human
Sample Type: Cell Culture Supernates
Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies.
Authors: Jotwani R, Palucka AK, Al-Quotub M, Nouri-Shirazi M, Kim J, Bell D, Banchereau J, Cutler CW
J. Immunol., 2001;167(8):4693-700.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
Natural interferon alpha/beta-producing cells link innate and adaptive immunity.
Authors: Kadowaki N, Antonenko S, Lau JY, Liu YJ
J. Exp. Med., 2000;192(2):219-26.
Species: Human
Sample Type: Cell Culture Supernates
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