| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
J Leukoc Biol, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates
Freeze-Dried Platelet-Rich Plasma Accelerates Bone Union with Adequate Rigidity in Posterolateral Lumbar Fusion Surgery Model in Rats
Sci Rep, 2016;6(0):36715.
Species: Rat
Sample Type: Plasma
Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury
Mol Med Rep, 2016;14(6):5556-5566.
Species: Mouse
Sample Type: Tissue Homogenates
TGF-? and Physiological Root Resorption of Deciduous Teeth
Int J Mol Sci, 2016;18(1):.
Species: Porcine
Sample Type: Tissue Extracts
Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution
Nat Commun, 2016;7(0):12177.
Species: Mouse
Sample Type: Peritoneal Fluid
P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
Stem Cell Res Ther, 2016;7(1):175.
Species: Mouse
Sample Type: Cell Culture Supernates
Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
Sci Rep, 2016;6(0):36077.
Species: Rat
Sample Type: Cell Culture Supernates
TGF-?1 autocrine signalling and enamel matrix components
Sci Rep, 2016;6(0):33644.
Species: Porcine
Sample Type:
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge
PLoS ONE, 2016;11(8):e0161169.
Species: Canine
Sample Type: Cell Culture Supernates
Tolerogenic Phenotype of IFN-?-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop
Authors: Qingsheng Li
J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells
CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage
Sci Rep, 2016;6(0):26239.
Species: Rat
Sample Type: Serum
High Physiological Concentrations of Progesterone Reverse Estradiol-Mediated Changes in Differentiation and Functions of Bone Marrow Derived Dendritic Cells
Authors: F Xiu, VC Anipindi, PV Nguyen, J Boudreau, H Liang, Y Wan, DP Snider, C Kaushic
PLoS ONE, 2016;11(4):e0153304.
Species: Mouse
Sample Type: Cell Culture Supernates
Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) as a Biomarker in the Mouse Model of Experimental Autoimmune Myocarditis (EAM)
PLoS ONE, 2016;11(8):e0158299.
Species: Mouse
Sample Type: Tissue Homogenates
TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
PLoS ONE, 2016;11(4):e0153811.
Species: Mouse
Sample Type: Serum
Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin
Respir. Res, 2016;17(1):162.
Species: Mouse
Sample Type: Pleural Lavage
Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis
PLoS ONE, 2016;11(12):e0163187.
Species: Rat
Sample Type: Cell Culture Supernates
Alcohol inhibits osteopontin-dependent transforming growth factor-beta1 expression in human mesenchymal stem cells.
Authors: Driver J, Weber C, Callaci J, Kothari A, Zapf M, Roper P, Borys D, Franzen C, Gupta G, Wai P, Zhang J, Denning M, Kuo P, Mi Z
J Biol Chem, 2015;290(16):9959-73.
Species: Mouse
Sample Type: Tissue Homogenates
Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat.
Authors: Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, Honda M, Inoue K, Saito M
PLoS ONE, 2015;10(8):e0133798.
Species: Rat
Sample Type: Tissue Homogenates
Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
J Immunol, 2015;194(11):5407-16.
Species: Mouse
Sample Type: BALF
Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.
Authors: Strobel B, Klauser B, Hartig J, Lamla T, Gantner F, Kreuz S
Mol Ther, 2015;23(10):1582-91.
Species: Human
Sample Type: Cell Culture Supernates
Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.
Authors: Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F
PLoS ONE, 2015;10(4):e0124048.
Species: Rat
Sample Type: Serum
AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4.
Authors: Xiao L, Peng X, Liu F, Tang C, Hu C, Xu X, Wang M, Luo Y, Yang S, Song P, Xiao P, Kanwar Y, Sun L
BMC Cell Biol, 2015;16(0):7.
Species: Mouse
Sample Type: Peritoneal Dialysate
MDSC and TGFbeta Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes.
Authors: Shvedova A, Kisin E, Yanamala N, Tkach A, Gutkin D, Star A, Shurin G, Kagan V, Shurin M
Cancer Res, 2015;75(8):1615-23.
Species: Mouse
Sample Type: Cell Culture Supernates
GP96 is a GARP chaperone and controls regulatory T cell functions.
Authors: Zhang Y, Wu B, Metelli A, Thaxton J, Hong F, Rachidi S, Ansa-Addo E, Sun S, Vasu C, Yang Y, Liu B, Li Z
J Clin Invest, 2015;125(2):859-69.
Species: Mouse
Sample Type: Serum
Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR.
Authors: Gregorini M, Corradetti V, Rocca C, Pattonieri E, Valsania T, Milanesi S, Serpieri N, Bedino G, Esposito P, Libetta C, Avanzini M, Mantelli M, Ingo D, Peressini S, Albertini R, Dal Canton A, Rampino T
PLoS ONE, 2015;11(2):e0148542.
Species: Rat
Sample Type: Tissue Homogenates
WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
BMC Gastroenterol, 2015;15(0):173.
Species: Mouse
Sample Type: Cell Culture Supernates
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
Authors: Charolidi N, Schilling T, Eder C
PLoS ONE, 2015;10(5):e0128463.
Species: Mouse
Sample Type: Cell Culture Supernates
Low TGFbeta1 expression prevents and high expression exacerbates diabetic nephropathy in mice.
Authors: Hathaway C, Gasim A, Grant R, Chang A, Kim H, Madden V, Bagnell C, Jennette J, Smithies O, Kakoki M
Proc Natl Acad Sci U S A, 2015;112(18):5815-20.
Species: Mouse
Sample Type: Plasma
Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.
Authors: Maneva-Radicheva L, Amatya C, Parker C, Ellefson J, Radichev I, Raghavan A, Charles M, Williams M, Robbins M, Savinov A
PLoS ONE, 2014;9(9):e107213.
Species: Mouse
Sample Type: Serum
Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10.
Authors: Nitahara-Kasahara Y, Hayashita-Kinoh H, Chiyo T, Nishiyama A, Okada H, Takeda S, Okada T
Hum Mol Genet, 2014;23(15):3990-4000.
Species: Mouse
Sample Type: Homogenized Tissue
The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis.
Authors: Zhang L, Hao J, Ren L, Ding J, Hao L
Lab Invest, 2014;94(8):839-50.
Species: Rat
Sample Type: Abdominal Cavity Liquid
Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis.
Authors: Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A
J Immunol, 2014;193(5):2330-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice.
Authors: Kikuchi, Yosuke, Kunitoh-Asari, Ayami, Hayakawa, Katsuyuk, Imai, Shinjiro, Kasuya, Kenji, Abe, Kimio, Adachi, Yu, Fukudome, Shin-Ich, Takahashi, Yoshimas, Hachimura, Satoshi
PLoS ONE, 2014;9(1):e86416.
Species: Mouse
Sample Type: Cell Culture Supernates
Antitumor activity of total flavonoids from Tetrastigma hemsleyanum Diels et Gilg is associated with the inhibition of regulatory T cells in mice.
Authors: Feng Z, Hao W, Lin X, Fan D, Zhou J
Onco Targets Ther, 2014;7(0):947-56.
Species: Mouse
Sample Type: Serum
Integrin-mediated type II TGF-beta receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.
Authors: Chen X, Wang H, Liao H, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang Z, Vega-Montoto L, Vanacore R, Fassler R, Zent R, Pozzi A
J Clin Invest, 2014;124(8):3295-310.
Species: Mouse
Sample Type: Tissue Homogenates
Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
FASEB J, 2014;28(4):1756-68.
Species: Mouse
Sample Type: Cell Culture Supernates
Pivotal role of phospholipase D1 in tumor necrosis factor-alpha-mediated inflammation and scar formation after myocardial ischemia and reperfusion in mice.
Authors: Schonberger T, Jurgens T, Muller J, Armbruster N, Niermann C, Gorressen S, Sommer J, Tian H, di Paolo G, Scheller J, Fischer J, Gawaz M, Elvers M
Am J Pathol, 2014;184(9):2450-64.
Species: Mouse
Sample Type: Cell Culture Supernates
Magnetic resonance colonography for fibrosis assessment in rats with chronic colitis.
Authors: Melchior C, Loeuillard E, Marion-Letellier R, Nicol L, Mulder P, Guerin C, Bole-Feysot C, Aziz M, Dechelotte P, Vera P, Savoye G, Savoye-Collet C
PLoS ONE, 2014;9(7):e100921.
Species: Rat
Sample Type: tissue homogenate supernatant
Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat.
Authors: Lu Q, Gao L, Huang L, Ruan L, Yang J, Huang W, Li Z, Zhang Y, Jin K, ZhuGe Q
J Neuroinflammation, 2014;11(0):44.
Species: Rat
Sample Type: Serum
FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis.
Authors: Ding Q, Cai G, Hu M, Yang Y, Zheng A, Tang Q, Gladson C, Hayasaka H, Wu H, You Z, Southern B, Grove L, Rahaman S, Fang H, Olman M
Am J Pathol, 2013;182(5):1572-84.
Species: Mouse
Sample Type: Tissue Supernates
Conditional expression of TGF-beta1 in skeletal muscles causes endomysial fibrosis and myofibers atrophy.
Authors: Narola J, Pandey S, Glick A, Chen Y
PLoS ONE, 2013;8(11):e79356.
Species: Mouse
Sample Type: Homogenized Tissue
Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
PLoS ONE, 2013;8(11):e81090.
Species: Mouse
Sample Type: BALF
Antifibrotic effects of a recombinant adeno-associated virus carrying small interfering RNA targeting TIMP-1 in rat liver fibrosis.
Authors: Cong M, Liu T, Wang P, Fan X, Yang A, Bai Y, Peng Z, Wu P, Tong X, Chen J, Li H, Cong R, Tang S, Wang B, Jia J, You H
Am J Pathol, 2013;182(5):1607-16.
Species: Rat
Sample Type: Serum
Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes.
Authors: Cabrera S, Colvin S, Tersey S, Maier B, Nadler J, Mirmira R
Clin Exp Immunol, 2013;172(3):375-82.
Species: Mouse
Sample Type: Serum
Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating beta-glucan.
Authors: Lipinski T, Fitieh A, St Pierre J, Ostergaard H, Bundle D, Touret N
J Immunol, 2013;190(8):4116-28.
Species: Mouse
Sample Type: Cell Culture Supernates
The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone.
Authors: Cho S, Pirih F, Koh A, Michalski M, Eber M, Ritchie K, Sinder B, Oh S, Al-Dujaili S, Lee J, Kozloff K, Danciu T, Wronski T, McCauley L
J Biol Chem, 2013;288(10):6814-25.
Species: Mouse
Sample Type: Cell Culture Supernates
CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.
Authors: Renson P, Le Dimna M, Keranflech A, Cariolet R, Koenen F, Le Potier M
Vet Res, 2013;44(0):9.
Species: Porcine
Sample Type: Serum
Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.
Authors: Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira F, Reis F
Cardiovasc Diabetol, 2013;12(0):44.
Species: Rat
Sample Type: Serum
Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
J. Biol. Chem., 2012;287(20):16356-64.
Species: Mouse
Sample Type: Cell Culture Supernates
Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency.
Authors: Kawamura T, Ogawa Y, Nakamura Y
J. Clin. Invest., 2012;122(2):722-32.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis.
Authors: Muller AM, Jun E, Conlon H, Sadiq SA
BMC Neurosci, 2012;13(0):30.
Species: Mouse
Sample Type: Serum
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
Blood, 2012;120(13):2600-9.
Species: Mouse
Sample Type: tissue lysates
Comparison of the effect of calcium gluconate and batroxobin on the release of transforming growth factor beta 1 in canine platelet concentrates.
Authors: Silva R, Carmona J, Rezende C
BMC Vet Res, 2012;8(0):121.
Species: Canine
Sample Type: Plasma
Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
Authors: Rau CR, Hein K, Sattler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bahr M
Am. J. Pathol., 2012;178(4):1770-81.
Species: Rat
Sample Type: Tissue Homogenates
TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
Eur. J. Immunol., 2012;42(8):2087-99.
Species: Mouse
Sample Type: Cell Culture Supernates
Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection.
J. Virol., 2012;86(13):7060-71.
Species: Mouse
Sample Type: Serum
Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function.
Authors: Hall BE, Zheng C, Swaim WD, Cho A, Nagineni CN, Eckhaus MA, Flanders KC, Ambudkar IS, Baum BJ, Kulkarni AB
Lab. Invest., 2011;90(4):543-55.
Species: Mouse
Sample Type: Serum
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
Authors: Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
J. Clin. Invest., 2011;121(11):4548-66.
Species: Mouse
Sample Type: Plasma
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011;186(12):7144-55.
Species: Mouse
Sample Type: Cell Culture Supernates
Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
Authors: Diao J, Zhao J, Winter E
J. Immunol., 2011;186(9):5058-67.
Species: Mouse
Sample Type: Cell Culture Supernates
Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells.
Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR
J. Immunol., 2011;186(8):4967-72.
Species: Mouse
Sample Type: Serum
Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model.
Authors: Shevalye H, Stavniichuk R, Xu W, Zhang J, Lupachyk S, Maksimchyk Y, Drel VR, Floyd EZ, Slusher B, Obrosova IG
Biochem. Pharmacol., 2010;79(7):1007-14.
Species: Rat
Sample Type: Tissue Homogenates
Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.
Authors: Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ
Nat. Med., 2010;16(2):191-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
Authors: Cash JL, Christian AR, Greaves DR
J. Immunol., 2010;184(9):5315-24.
Species: Mouse
Sample Type: Cell Culture Supernates
Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
Species: Mouse
Sample Type: BALF
Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
Authors: Yoshizaki A, Yanaba K, Iwata Y
J. Immunol., 2010;185(4):2502-15.
Species: Mouse
Sample Type: Serum
Anti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-gamma, but not transforming growth factor-beta dependent.
Authors: Srivastava K, Zhang T, Yang N, Sampson H, Li XM
Clin. Exp. Allergy, 2010;40(11):1678-88.
Species: Mouse
Sample Type: BALF
Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
Authors: Graham BB, Mentink-Kane MM, El-Haddad H
Am. J. Pathol., 2010;177(3):1549-61.
Species: Mouse
Sample Type: Tissue Homogenates
Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2010;130(3):866-75.
Species: Mouse
Sample Type: Tissue Homogenates
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2009;21(1):81-93.
Species: Mouse
Sample Type: Tissue Homogenates
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
Species: Mouse
Sample Type: BALF
Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
J. Immunol., 2009;182(11):6907-14.
Species: Mouse
Sample Type: BALF
Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
Authors: Izumo T, Kondo M, Nagai A
Eur. Respir. J., 2009;34(6):1444-51.
Species: Mouse
Sample Type: BALF
Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
Authors: Bhowmick S, Mazumdar T, Ali N
Infect. Immun., 2009;77(4):1514-23.
Species: Mouse
Sample Type: Cell Culture Supernates
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
Authors: Koronyo-Hamaoui M, Ko MK, Koronyo Y, Azoulay D, Seksenyan A, Kunis G, Pham M, Bakhsheshian J, Rogeri P, Black KL, Farkas DL, Schwartz M
J. Neurochem., 2009;111(6):1409-24.
Species: Mouse
Sample Type: Tissue Homogenates
Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma.
Authors: Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C
Am. J. Respir. Crit. Care Med., 2009;179(10):894-902.
Species: Mouse
Sample Type: Tissue Homogenates
Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.
Authors: Nicola T, Hagood JS, James ML, Macewen MW, Williams TA, Hewitt MM, Schwiebert L, Bulger A, Oparil S, Chen YF, Ambalavanan N
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L738-50.
Species: Mouse
Sample Type: Tissue Homogenates
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009;208(1):54-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy.
Authors: Schuleri KH, Feigenbaum GS, Centola M, Weiss ES, Zimmet JM, Turney J, Kellner J, Zviman MM, Hatzistergos KE, Detrick B, Conte JV, McNiece I, Steenbergen C, Lardo AC, Hare JM
Eur. Heart J., 2009;30(22):2722-32.
Species: Porcine
Sample Type: Serum
Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma.
Authors: Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC
Am. J. Respir. Cell Mol. Biol., 2009;40(3):349-58.
Species: Mouse
Sample Type: BALF
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
Int. Immunol., 2009;21(5):555-65.
Species: Mouse
Sample Type: Peritoneal Lavage
Poly(Adenosine 5-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy.
Authors: Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG
Endocrinology, 2009;150(12):5273-83.
Species: Rat
Sample Type: Tissue Homogenates
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008;22(7):2198-205.
Species: Mouse
Sample Type: Plasma
Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008;38(10):2751-61.
Species: Mouse
Sample Type: BALF
Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
Eur. J. Immunol., 2008;38(5):1358-67.
Species: Mouse
Sample Type: Cell Culture Supernates
Observations on the microvasculature of bone defects filled with biodegradable nanoparticulate hydroxyapatite.
Authors: Kilian O, Wenisch S, Karnati S, Baumgart-Vogt E, Hild A, Fuhrmann R, Jonuleit T, Dingeldein E, Schnettler R, Franke RP
Biomaterials, 2008;29(24):3429-37.
Species: Porcine
Sample Type: Plasma
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
Vaccine, 2008;26(33):4237-43.
Species: Mouse
Sample Type: Cell Culture Supernates
Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
J. Leukoc. Biol., 2008;83(5):1136-44.
Species: Mouse
Sample Type: Cell Culture Supernates
Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.
Authors: Lau AW, Biester S, Cornall RJ, Forrester JV
J. Immunol., 2008;180(6):3889-99.
Species: Mouse
Sample Type: Cell Culture Supernates
Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
Authors: Yamazaki T, Nagata K, Kobayashi Y
Cell. Immunol., 2008;251(2):124-30.
Species: Mouse
Sample Type: Cell Culture Supernates
Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.
Authors: Ishida Y, Gao JL, Murphy PM
J. Immunol., 2008;180(1):569-79.
Species: Mouse
Sample Type: Tissue Homogenates
Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
Proc. Natl. Acad. Sci. U.S.A., 2008;105(20):7240-5.
Species: Mouse
Sample Type: BALF
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
Eur. J. Pharmacol., 2008;590(1):400-8.
Species: Mouse
Sample Type: Tissue Homogenates
Oridonin promotes CD4+/CD25+ Treg differentiation, modulates Th1/Th2 balance and induces HO-1 in rat splenic lymphocytes.
Authors: Hu AP, Du JM, Li JY, Liu JW
Inflamm. Res., 2008;57(4):163-70.
Species: Rat
Sample Type: Cell Culture Supernates
Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
Authors: Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A
Diabetes, 2008;57(8):2107-17.
Species: Mouse
Sample Type: Cell Culture Supernates
A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis.
Authors: Morschl E, Molina JG, Volmer JB, Mohsenin A, Pero RS, Hong JS, Kheradmand F, Lee JJ, Blackburn MR
Am. J. Respir. Cell Mol. Biol., 2008;39(6):697-705.
Species: Mouse
Sample Type: BALF
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
J. Immunol., 2008;181(2):1491-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.
Authors: Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS
J. Clin. Invest., 2008;118(2):479-90.
Species: Mouse
Sample Type: Cell Culture Supernates
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
Authors: Shweke N, Boulos N, Jouanneau C, Vandermeersch S, Melino G, Dussaule JC, Chatziantoniou C, Ronco P, Boffa JJ
Am. J. Pathol., 2008;173(3):631-42.
Species: Mouse
Sample Type: Tissue Homogenates
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
Authors: Guo B, Chang EY, Cheng G
J. Clin. Invest., 2008;118(5):1680-90.
Species: Mouse
Sample Type: Cell Culture Supernates
Molecular mechanisms of TGFbeta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Authors: Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
J. Immunol., 2008;181(4):2831-45.
Species: Rat
Sample Type: Urine
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
J. Immunol., 2008;180(1):522-9.
Species: Mouse
Sample Type: BALF
A new murine model for bronchiolitis obliterans post-bone marrow transplant.
Authors: Panoskaltsis-Mortari A, Tram KV, Price AP, Wendt CH, Blazar BR
Am. J. Respir. Crit. Care Med., 2007;176(7):713-23.
Species: Mouse
Sample Type: Serum
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Authors: Izumo T, Kondo M, Nagai A
Life Sci., 2007;80(20):1882-6.
Species: Mouse
Sample Type: BALF
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
J. Clin. Invest., 2007;117(12):3786-99.
Species: Mouse
Sample Type: BALF
Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Authors: Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG
Mol. Cell. Biol., 2007;27(4):1356-69.
Species: Mouse
Sample Type: Cell Culture Supernates
Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo.
Authors: Poncelet AJ, Vercruysse J, Saliez A, Gianello P
Transplantation, 2007;83(6):783-90.
Species: Porcine
Sample Type: Cell Culture Supernates
T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.
Authors: Farini A, Meregalli M, Belicchi M, Battistelli M, Parolini D, DAntona G, Gavina M, Ottoboni L, Constantin G, Bottinelli R, Torrente Y
J. Pathol., 2007;213(2):229-38.
Species: Mouse
Sample Type: Tissue Homogenates
Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
Immunology, 2007;122(2):268-78.
Species: Mouse
Sample Type: BALF
Characterization of in vitro antimurine thymocyte globulin-induced regulatory T cells that inhibit graft-versus-host disease in vivo.
Authors: Ruzek MC, Waire JS, Hopkins D, Lacorcia G, Sullivan J, Roberts BL, Richards SM, Nahill SR, Williams JM, Scaria A, Dzuris J, Shankara S, Garman RD
Blood, 2007;111(3):1726-34.
Species: Mouse
Sample Type: Cell Culture Supernates
The role of the receptor for advanced glycation end-products in lung fibrosis.
Authors: He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H, Yamaya M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(6):L1427-36.
Species: Mouse
Sample Type: BALF
Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR
J. Immunol., 2007;178(2):851-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
Authors: Socha MJ, Manhiani M, Said N, Imig JD, Motamed K
Am. J. Pathol., 2007;171(4):1104-12.
Species: Mouse
Sample Type: Cell Culture Supernates
Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model.
Authors: Koyanagi T, Noguchi K, Ootani A, Inagaki K, Robbins RC, Mochly-Rosen D
J. Mol. Cell. Cardiol., 2007;43(4):517-22.
Species: Mouse
Sample Type: Tissue Homogenates
Liposomal retinoic acids modulate asthma manifestations in mice.
Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
J. Nutr., 2007;137(12):2730-6.
Species: Mouse
Sample Type: BALF
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
Blood, 2007;111(1):219-28.
Species: Mouse
Sample Type: Cell Culture Supernates
Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma.
Authors: Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK, Lee YC
J. Immunol., 2006;177(8):5248-57.
Species: Mouse
Sample Type: BALF
Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy.
Authors: Li J, Campanale NV, Liang RJ, Deane JA, Bertram JF, Ricardo SD
Am. J. Pathol., 2006;169(5):1527-40.
Species: Mouse
Sample Type: Tissue Homogenates
Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.
Authors: Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R
Arthritis Rheum., 2006;54(10):3363-71.
Species: Mouse
Sample Type: Peritoneal Lavage
Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
Biosci. Biotechnol. Biochem., 2006;70(8):2013-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane.
Authors: Noh H, Kim JS, Han KH, Lee GT, Song JS, Chung SH, Jeon JS, Ha H, Lee HB
Kidney Int., 2006;69(11):2022-8.
Species: Rat
Sample Type: Tissue Homogenates
Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.
Authors: Garantziotis S, Brass DM, Savov J, Hollingsworth JW, McElvania-TeKippe E, Berman K, Walker JK, Schwartz DA
Am. J. Respir. Cell Mol. Biol., 2006;35(6):662-7.
Species: Mouse
Sample Type: Lung Lavage
Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
Authors: Greber B, Lehrach H, Adjaye J
Stem Cells, 2006;25(2):455-64.
Species: Mouse
Sample Type: Cell Culture Supernates
Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006;54(10):3182-93.
Species: Mouse
Sample Type: Tissue Homogenates
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Authors: Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK
J. Cell. Biochem., 2006;97(5):1036-51.
Species: Mouse
Sample Type: Serum
Inhaled nitric oxide improves the survival of the paraquat-injured rats.
Authors: Cho JH, Yang DK, Kim L, Ryu JS, Lee HL, Lim CM, Koh YS
Vascul. Pharmacol., 2005;42(4):171-8.
Species: Rat
Sample Type: Serum
Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
Anticancer Res., 2005;25(1):299-303.
Species: Mouse
Sample Type: Peritoneal Exudate
Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
Authors: Akool el-S, Doller A, Muller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W
J. Biol. Chem., 2005;280(47):39403-16.
Species: Rat
Sample Type: Cell Culture Supernates
Measurement of bone morphogenetic proteins and other growth factors in demineralized bone matrix.
Authors: Blum B, Moseley J, Miller L, Richelsoph K, Haggard W
Orthopedics, 2004;27(1):161-5.
Species: Human
Sample Type: Tissue Homogenates
Suppression of cytokine-inducible nitric oxide synthesis during intraperitoneal Meth A tumor growth.
Authors: Kwon OD, Yim CY, Jeong KS, Park SC, Jung KY, McGregor JR, Bastian NR, Samlowski WE
J. Vet. Med. Sci., 2004;66(5):357-65.
Species: Mouse
Sample Type: Ascites
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004;199(10):1355-65.
Species: Mouse
Sample Type: Serum
Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung.
Authors: Bechara RI, Brown LA, Roman J, Joshi PC, Guidot DM
Am. J. Respir. Crit. Care Med., 2004;170(2):188-94.
Species: Rat
Sample Type: Tissue Homogenates
Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice.
Authors: Kobayashi T, Iijima K, Kita H
J. Immunol., 2003;170(11):5756-63.
Species: Mouse
Sample Type: BALF
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