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货号: bs-7799R-Cy5.5 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-7799R-Cy5.5
- 英文名称
- Anti-MND1/Cy5.5
- 中文名称
- Cy5.5标记的减数分裂核分裂蛋白1/GAJ抗体
- 别 名
- GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1309007; 2610034E18Rik; AI591601.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞周期蛋白 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GAJ/MND1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
Function:
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
Subunit:
Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA.
Subcellular Location:
Nucleus (Probable)
Similarity:
Belongs to the MND1 family.
Database links:
UniProtKB/Swiss-Prot: Q9BWT6.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.