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Rat IFN-gamma Quantikine SixPak (6 Plates) (1 PK)

货号: SRIF00 基本售价: 30090.6 元 规格: 1 PACK

产品信息

概述
货号SRIF00
描述The Quantikine Rat IFN-gamma Immunoassay is a 4.5 hour solid phase ELISA designed to measure rat IFN-gamma levels in cell culture supernates and serum. It contains E. coli-expressed recombinant rat IFN-gamma and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant rat IFN-gamma accurately. Results obtained using natural rat IFN-gamma showed dose curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural rat IFN-gamma.
别名IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma;
全称
Interferon gamma
反应种属Rat
目标/特异性Natural and recombinant rat IFN-gamma
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.
Authors: Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F
PLoS ONE, 2015;10(4):e0124048.
Species: Rat
Sample Type: Serum

Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F
BMC Cancer, 2015;15(0):34.
Species: Rat
Sample Type: Tissue Supernate

Oridonin promotes CD4+/CD25+ Treg differentiation, modulates Th1/Th2 balance and induces HO-1 in rat splenic lymphocytes.
Authors: Hu AP, Du JM, Li JY, Liu JW
Inflamm. Res., 2008;57(4):163-70.
Species: Rat
Sample Type: Cell Culture Supernates

Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1183-93.
Species: Rat
Sample Type: BALF

Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat.
Authors: Sheikh N, Dudas J, Ramadori G
Lab. Invest., 2007;87(7):713-25.
Species: Rat
Sample Type: Serum

The age-related attenuation in long-term potentiation is associated with microglial activation.
Authors: Griffin R, Nally R, Nolan Y, McCartney Y, Linden J, Lynch MA
J. Neurochem., 2006;99(4):1263-72.
Species: Rat
Sample Type: Tissue Homogenates

Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.
Authors: Gegg ME, Harry R, Hankey D, Zambarakji H, Pryce G, Baker D, Adamson P, Calder V, Greenwood J
J. Immunol., 2005;174(4):2327-35.
Species: Rat
Sample Type: Cell Culture Supernates

Immunotherapy of murine prostate cancer using whole tumour cells killed ex vivo by cytosine deaminase/5-fluorocytosine suicide-gene therapy.
Authors: Pandha HS, Cook D, Greenhalgh R, Dalgleish A
BJU Int., 2005;95(9):1336-43.
Species: Rat
Sample Type: Cell Culture Supernates

Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.
Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B
Crit. Care Med., 2005;33(10):2317-22.
Species: Rat
Sample Type: BALF

Effects of pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, on cytokine expression and ocular inflammation in experimental autoimmune anterior uveitis.
Authors: Fang IM, Yang CH, Lin CP, Yang CM, Chen MS
J Ocul Pharmacol Ther, 2005;21(2):95-106.
Species: Rat
Sample Type: Aqueous humor

Salivary gland genetic vaccination: a scalable technology for promoting distal mucosal immunity and heightened systemic immune responses.
Authors: Tucker SN, Lin K, Stevens S, Scollay R, Bennett MJ, Olson DC
Vaccine, 2004;22(19):2500-4.
Species: Rat
Sample Type: Cell Culture Supernates

Ameliorating effects of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole in an experimental model of colitis in the rat.
Authors: Stasi MA, Ruggiero V, Ursillo A, Taurelli R, Agliano M, Weber E, Lorenzoni P, Sorrentino V, Pacifici L, Carminati P
Eur. J. Pharmacol., 2004;494(2):263-72.
Species: Rat
Sample Type: Tissue Homogenates

Alveolar macrophage cytotoxicity for normal lung fibroblasts is mediated by nitric oxide release.
Authors: Morgan DL, Shines CJ
Toxicol In Vitro, 2004;18(1):139-46.
Species: Rat
Sample Type: Cell Culture Supernates

Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells.
Authors: Yuan Z, Liu Y, Liu Y, Zhang J, Kishimoto C, Ma A, Liu Z
J. Cardiovasc. Pharmacol., 2004;43(6):868-75.
Species: Rat
Sample Type:

Gene transfer of tumor necrosis factor inhibitor improves the function of lung allografts.
Authors: Tagawa T, Kozower BD, Kanaan SA, Daddi N, Muraoka M, Oka T, Ritter JH, Patterson GA
J. Thorac. Cardiovasc. Surg., 2004;127(6):1558-63.
Species: Rat
Sample Type: Tissue Homogenates

Melatonin fails to modulate immune parameters influenced by calorie restriction in aging Fischer 344 rats.
Authors: Pahlavani MA, Vargas DA, Evans TR, Shu JH, Nelson JF
Exp. Biol. Med. (Maywood), 2002;227(3):201-7.
Species: Rat
Sample Type: Cell Culture Supernates

Recipient intramuscular cotransfection of naked plasmid transforming growth factor beta1 and interleukin 10 ameliorates lung graft ischemia-reperfusion injury.
Authors: D'Ovidio F
J. Thorac. Cardiovasc. Surg., 2002;124(2):259-69.
Species: Rat
Sample Type: Lung Lavage

Chimeric smooth muscle-specific enhancer/promoters: valuable tools for adenovirus-mediated cardiovascular gene therapy.
Authors: Ribault S, Neuville P, Mechine-Neuville A, Auge F, Parlakian A, Gabbiani G, Paulin D, Calenda V
Circ. Res., 2001;88(5):468-75.
Species: Rat
Sample Type: Cell Culture Supernates

Role of IL-18 in acute lung inflammation.
Authors: Jordan JA, Guo RF, Yun EC, Sarma V, Warner RL, Crouch LD, Senaldi G, Ulich TR, Ward PA
J. Immunol., 2001;167(12):7060-8.
Species: Rat
Sample Type: BALF

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
运输条件Blue Ice
存放说明4℃
参考文献
  • Conventional/Classical Dendritic Cells
  • Cytokines and Receptors in Allergy and Asthma
  • Cytokines and Receptors in Angiogenesis
  • Cytokines and Receptors in Tfh Cell Differentiation and Function
  • gamma delta T Cells
  • Group 1 ILCs
  • IL-10/Interferon Family
  • Infectious Diseases
  • Inflammatory Mediators
  • Isolation, Culture, and Identification of Natural Killer Cells
  • Macrophage Activation Markers
  • Molecules Secreted by VSMC
  • Multiple Sclerosis and Myelin Related Molecules
  • Myeloid-derived Suppressor Cells (MDSC)
  • Natural Killer T (NKT) Cells
  • NCR+ILC3
  • NCR-ILC3
  • Neuroinflammation
  • Regulatory T Cells (Tregs)
  • T Cell Cytokine Signaling
  • Th1 Cells