R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats Authors: KH Seo, JW Choi, HS Jung, H Yoo, JD Joo J. Korean Med. Sci, 2017;32(3):542-551. Species: Rat Sample Type: Serum
The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure. Authors: Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, Grenier N, Drouet M, Herodin F PLoS ONE, 2015;10(4):e0122900. Species: Rats Sample Type: Plasma
Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy. Authors: Ahmed M, Kumar G, Navarro G, Wang Y, Gourevitch S, Moussa M, Rozenblum N, Levchenko T, Galun E, Torchilin V, Goldberg S PLoS ONE, 2015;10(7):e0128910. Species: Rat Sample Type: Serum
Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat. Authors: Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, Honda M, Inoue K, Saito M PLoS ONE, 2015;10(8):e0133798.
Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model. Authors: Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F PLoS ONE, 2015;10(4):e0124048. Species: Rat Sample Type: Serum
IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation. Authors: Sun J, Zhang S, Zhang X, Zhang X, Dong H, Qian Y J Neuroinflammation, 2015;12(0):165.
Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer. Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F BMC Cancer, 2015;15(0):34. Species: Rat Sample Type: Tissue Supernate
Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca(2+) signals and an IL-6 autocrine loop. Authors: Bustamante M, Fernandez-Verdejo R, Jaimovich E, Buvinic S Am J Physiol Endocrinol Metab, 2014;306(8):E869-82. Species: Rat Sample Type: Cell Culture Supernates
Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat. Authors: Wang Z, Huang W, Zuo Z J Neuroinflammation, 2014;11(0):56. Species: Rat Sample Type: Whole Tissue
Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission. Authors: Shinozaki Y, Nomura M, Iwatsuki K, Moriyama Y, Gachet C, Koizumi S Sci Rep, 2014;4(0):4329. Species: Rat Sample Type: Cell Culture Supernates
Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3. Authors: Wilson C, Mann J, Walsh M, Perrugoria M, Oakley F, Wright M, Brignole C, Di Paolo D, Perri P, Ponzoni M, Karin M, Mann D PLoS ONE, 2014;9(1):e83391. Species: Rat Sample Type: Cell Culture Supernates
Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B. Authors: Xiao W, Yin G, Fan Y, Qiu L, Cang X, Yu G, Hu Y, Xing M, Wu D, Wang X, Hu G, Wan R Int J Mol Sci, 2014;15(7):11957-72. Species: Rat Sample Type: Serum
Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model. Authors: Ding N, Wang F, Xiao H, Xu L, She S PLoS ONE, 2013;8(9):e74633. Species: Rat Sample Type: BALF
Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker. Authors: Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira F, Reis F Cardiovasc Diabetol, 2013;12(0):44. Species: Rat Sample Type: Serum
A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion. Cytokine, 2013;61(2):614-21. Species: Rat Sample Type: BALF
Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. Authors: Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, Van Dyck C Lab Invest, 2012;92(10):1428-39. Species: Rat Sample Type: Serum
Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain. J Neuroinflammation, 2012;9(0):181. Species: Rat Sample Type: Tissue Homogenates
Vipera aspis venom reduces lethality and down-regulates tumor necrosis factor-alpha in a rat model of LPS-induced sepsis. Authors: Frolkis I, Klein Y, Locker C, Adi N, Dahan E, Uretzsky G, Shapira I, Sorkine P Cytokine, 2010;49(3):319-24. Species: Rat Sample Type: Serum
In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland. Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM Brain Behav. Immun., 2009;23(7):945-57. Species: Rat Sample Type: Plasma
Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses. Authors: Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH J. Leukoc. Biol., 2009;85(6):1015-26. Species: Rat Sample Type: Serum
Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis. Authors: Costello J, Higgins B, Contreras M, Chonghaile MN, Hassett P, OToole D, Laffey JG Crit. Care Med., 2009;37(8):2412-20. Species: Rat Sample Type: BALF
Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha. Authors: Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, Wang P, Messina JL Endocrinology, 2008;149(5):2369-82. Species: Rat Sample Type: Serum
JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat. Authors: Dominguez E, Rivat C, Pommier B, Mauborgne A, Pohl M J. Neurochem., 2008;107(1):50-60. Species: Rat Sample Type: Tissue Homogenates
Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge. Authors: Johnson JD, Cortez V, Kennedy SL, Foley TE, Hanson H, Fleshner M Brain Behav. Immun., 2008;22(7):1078-86. Species: Rat Sample Type: Plasma
Induction of type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone. Authors: Sanchez E, Singru PS, Fekete C, Lechan RM Endocrinology, 2008;149(5):2484-93. Species: Rat Sample Type: Serum
Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications. Authors: Wojcikowski J, Golembiowska K, Daniel WA Biochem. Pharmacol., 2008;76(2):258-67. Species: Rat Sample Type: Plasma
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. Authors: Choi G, Hofstra JJ, Roelofs JJ, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ Crit. Care Med., 2008;36(1):204-10. Species: Rat Sample Type: BALF
Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation. Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1183-93. Species: Rat Sample Type: BALF
Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat. Authors: Sheikh N, Dudas J, Ramadori G Lab. Invest., 2007;87(7):713-25. Species: Rat Sample Type: Serum
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. Authors: Wosten-van Asperen RM, Lutter R, Haitsma JJ, Merkus MP, van Woensel JB, van der Loos CM, Florquin S, Lachmann B, Bos AP Eur. Respir. J., 2007;31(2):363-71. Species: Rat Sample Type: BALF
Cell-based angiopoietin-1 gene therapy for acute lung injury. Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ Am. J. Respir. Crit. Care Med., 2007;175(10):1014-26. Species: Rat Sample Type: BALF
Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation. Authors: Choi G, Vlaar AP, Schouten M, Vant Veer C, van der Poll T, Levi M, Schultz MJ Eur. Respir. J., 2007;30(3):423-8. Species: Rat Sample Type: Tissue Homogenates
Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. Authors: Yu HP, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH J. Leukoc. Biol., 2007;82(3):774-80. Species: Rat Sample Type: Tissue Homogenates
Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH J. Mol. Cell. Cardiol., 2007;42(3):620-30. Species: Rat Sample Type: Plasma
The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. Authors: Cao Z, Gao Y, Bryson JB, Hou J, Chaudhry N, Siddiq M, Martinez J, Spencer T, Carmel J, Hart RB, Filbin MT J. Neurosci., 2006;26(20):5565-73. Species: Rat Sample Type: Cell Culture Supernates
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Authors: Barkho BZ, Song H, Aimone JB Stem Cells Dev., 2006;15(3):407-21. Species: Rat Sample Type: Cell Culture Supernates
Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure. Authors: Holly MK, Dear JW, Hu X, Schechter AN, Gladwin MT, Hewitt SM, Yuen PS, Star RA Kidney Int., 2006;70(3):496-506. Species: Rat Sample Type: Serum
Glucosamine administration during resuscitation improves organ function after trauma hemorrhage. Authors: Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB Shock, 2006;25(6):600-7. Species: Rat Sample Type: Plasma
Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. Authors: Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S Invest. Ophthalmol. Vis. Sci., 2006;47(6):2686-92. Species: Rat Sample Type: Tissue Homogenates
Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis. Authors: Chen CC, Wang SS, Tsay SH, Lee FY, Lu RH, Chang FY, Lee SD Cytokine, 2006;33(2):95-9. Species: Rat Sample Type: Serum
Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B Crit. Care Med., 2005;33(10):2317-22. Species: Rat Sample Type: BALF
Developmental changes induced by graded prenatal systemic hypoxic-ischemic insults in rats. Authors: Robinson S, Petelenz K, Li Q, Cohen ML, Dechant A, Tabrizi N, Bucek M, Lust D, Miller RH Neurobiol. Dis., 2005;18(3):568-81. Species: Rat Sample Type: Amniotic Fluid
A method for measuring multiple cytokines from small samples. Authors: O'Connor KA Brain Behav. Immun., 2004;18(3):274-80. Species: Rat Sample Type: CSF
Insulin attenuates the systemic inflammatory response in endotoxemic rats. Authors: Jeschke MG, Klein D, Bolder U, Einspanier R Endocrinology, 2004;145(9):4084-93. Species: Rat Sample Type: Tissue Homogenates
Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma. Authors: Schubert T, Horch RE Ann. Surg., 2004;240(2):340-9. Species: Rat Sample Type: Tissue Homogenates
HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Authors: Holguin A, O'Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR Pain, 2004;110(3):517-30. Species: Rat Sample Type: CSF
Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor. Authors: Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Taylor AW Int. Immunopharmacol., 2004;4(8):1059-66. Species: Rat Sample Type: Aqueous humor
Differential expression of cytokine genes and inducible nitric oxide synthase induced by opacity phenotype variants of Streptococcus pneumoniae during acute otitis media in the rat. Authors: Long JP, Tong HH, Shannon PA, DeMaria TF Infect. Immun., 2003;71(10):5531-40. Species: Rat Sample Type: middle ear effusion
Iron intake increases infarct volume after permanent middle cerebral artery occlusion in rats. Authors: Castellanos M, Puig N, Carbonell T, Castillo J, Martinez J, Rama R, Davalos A Brain Res., 2002;952(1):1-6. Species: Rat Sample Type: Serum
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