R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Dose-dependency and reversibility of radiation-induced injury in cardiac explant-derived cells of mice Authors: L Luo, C Yan, Y Urata, AS Hasan, S Goto, CY Guo, S Zhang, TS Li Sci Rep, 2017;7(0):40959. Species: Mouse Sample Type: Cell Culture Supernates
Mosaic expression of Atrx in the mouse central nervous system causes memory deficits Authors: RJ Tamming, JR Siu, Y Jiang, MA Prado, F Beier, NG B?rub? Dis Model Mech, 2017;10(2):119-126. Species: Mouse Sample Type: Plasma
Metformin inhibits the proliferation of benign prostatic epithelial cells Authors: Z Wang, X Xiao, R Ge, J Li, CW Johnson, C Rassoulian, AF Olumi PLoS ONE, 2017;12(3):e0173335. Species: Mouse Sample Type: Cell Culture Supernates
Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth Authors: S Becker, H Wang, B Yu, R Brown, X Han, RH Lane, ME Hartnett Sci Rep, 2017;7(0):42301. Species: Rat Sample Type: Serum
Radiation Exposure Decreases the Quantity and Quality of Cardiac Stem Cells in Mice PLoS ONE, 2016;11(5):e0152179. Species: Mouse Sample Type: Cell culture media
Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart PLoS ONE, 2016;11(5):e0155611. Species: Mouse Sample Type: Plasma
Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine Sci Rep, 2016;6(0):31853. Species: Mouse Sample Type: Serum
IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction Authors: Thor Tejada Proc Natl Acad Sci USA, 2016;0(0):. Species: Mouse Sample Type: Serum
Single ingestion of soy ?-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects Authors: Tsutomu Hashidume Sci Rep, 2016;6(0):28183. Species: Mouse Sample Type: Serum
First steps to define murine amniotic fluid stem cell microenvironment Sci Rep, 2016;6(0):37080. Species: Mouse Sample Type: Amniotic Fluid
Positive Prehabilitative Effect of Intense Treadmill Exercise for Ameliorating Cancer Cachexia Symptoms in a Mouse Model J Cancer, 2016;7(15):2378-2387. Species: Mouse Sample Type: Plasma
Fibroblast growth factor 21 has no direct role in regulating fertility in female mice Mol Metab, 2016;5(8):690-8. Species: Mouse Sample Type: Plasma
The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats J Neuroinflammation, 2016;13(1):300. Species: Rat Sample Type: Serum
MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms. Authors: Conti V, Gandaglia A, Galli F, Tirone M, Bellini E, Campana L, Kilstrup-Nielsen C, Rovere-Querini P, Brunelli S, Landsberger N PLoS ONE, 2015;10(6):e0130183. Species: Mouse Sample Type: Plasma
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Authors: Baker D, Childs B, Durik M, Wijers M, Sieben C, Zhong J, Saltness R, Jeganathan K, Verzosa G, Pezeshki A, Khazaie K, Miller J, van Deursen J Nature, 2015;530(7589):184-9. Species: Mouse Sample Type: Serum
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. Authors: Charolidi N, Schilling T, Eder C PLoS ONE, 2015;10(5):e0128463. Species: Mouse Sample Type: Cell Culture Supernates
Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability. Authors: Nguyen K, Yao X, Erickson A, Mishra S, Nyomba B Endocrinology, 2015;156(2):462-74. Species: Mouse Sample Type: Serum
The order of concurrent endurance and resistance exercise modifies mTOR signaling and protein synthesis in rat skeletal muscle. Authors: Ogasawara R, Sato K, Matsutani K, Nakazato K, Fujita S Am J Physiol Endocrinol Metab, 2014;306(10):E1155-62. Species: Rat Sample Type: Serum
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice. Authors: Sapra, Geeta, Tham, Yow Keat, Cemerlang, Nelly, Matsumoto, Aya, Kiriazis, Helen, Bernardo, Bianca C, Henstridge, Darren C, Ooi, Jenny Y, Pretorius, Lynette, Boey, Esther J, Lim, Lydia, Sadoshima, Junichi, Meikle, Peter J, Mellet, Natalie, Woodcock, Elizabet, Marasco, Silvana, Ueyama, Tomomi, Du, Xiao-Jun, Febbraio, Mark A, McMullen, Julie R Nat Commun, 2014;5(0):5705. Species: Mouse Sample Type: Plasma
Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling. Authors: Hwang D, Shin H, Kwon M, Choi J, Ryu B, Kim B J Neurosci, 2014;34(38):12788-800. Species: Rat Sample Type: Serum
The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice. Authors: Kuno T, Hata K, Takamatsu M, Hara A, Hirose Y, Takahashi S, Imaida K, Tanaka T Int J Mol Sci, 2014;15(5):9160-72. Species: Mouse Sample Type: Plasma
Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine. Authors: Keipert S, Ost M, Johann K, Imber F, Jastroch M, van Schothorst E, Keijer J, Klaus S Am J Physiol Endocrinol Metab, 2014;306(5):E469-82. Species: Mouse Sample Type: Plasma
Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner. Authors: Harvey A, Lashinger L, Hays D, Harrison L, Lewis K, Fischer S, Hursting S PLoS ONE, 2014;9(5):e94151. Species: Mouse Sample Type: Serum
HGF signaling impacts severity of Pseudomonas aeruginosa keratitis. Authors: Jiang X, McClellan S, Barrett R, Foldenauer M, Hazlett L Invest Ophthalmol Vis Sci, 2014;55(4):2180-90. Species: Mouse Sample Type: Tissue Homogenates
Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast. Authors: Hirose J, Masuda H, Tokuyama N, Omata Y, Matsumoto T, Yasui T, Kadono Y, Hennighausen L, Tanaka S J Exp Med, 2014;211(1):153-63. Species: Mouse Sample Type: Serum
IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. Authors: Mellott T, Pender S, Burke R, Langley E, Blusztajn J PLoS ONE, 2014;9(4):e94287. Species: Mouse Sample Type: Tissue Homogenates
Long-term physiological alterations and recovery in a mouse model of separation associated with time-restricted feeding: a tool to study anorexia nervosa related consequences. Authors: Zgheib S, Mequinion M, Lucas S, Leterme D, Ghali O, Tolle V, Zizzari P, Bellefontaine N, Legroux-Gerot I, Hardouin P, Broux O, Viltart O, Chauveau C PLoS ONE, 2014;9(8):e103775. Species: Mouse Sample Type: Plasma
Overlapping dose responses of spermatogenic and extragonadal testosterone actions jeopardize the principle of hormonal male contraception. Authors: Oduwole O, Vydra N, Wood N, Samanta L, Owen L, Keevil B, Donaldson M, Naresh K, Huhtaniemi I FASEB J, 2014;28(6):2566-76. Species: Mouse Sample Type: Serum
Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength. Authors: Brisson, Becky K, Spinazzola, Janelle, Park, SooHyun, Barton, Elisabet Am J Physiol Endocrinol Metab, 2014;306(8):E965-74. Species: Mouse Sample Type: Tissue Homogenates
Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury. Authors: Piccioni A, Gaetani E, Palladino M, Gatto I, Smith R, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R Gene Ther, 2014;21(4):413-21. Species: Mouse Sample Type: cell supernates
The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone. Authors: Nuytens, Kim, Tuand, Krizia, Fu, Quili, Stijnen, Pieter, Pruniau, Vincent, Meulemans, Sandra, Vankelecom, Hugo, Creemers, John W M PLoS ONE, 2014;9(10):e109598. Species: Mouse Sample Type: Plasma
Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver. Authors: Fernandez-Perez L, Santana-Farre R, de Mirecki-Garrido M, Garcia I, Guerra B, Mateo-Diaz C, Iglesias-Gato D, Diaz-Chico J, Flores-Morales A, Diaz M PLoS ONE, 2014;9(5):e96305. Species: Rat Sample Type: Serum
IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells. Authors: Osuka S, Sampetrean O, Shimizu T, Saga I, Onishi N, Sugihara E, Okubo J, Fujita S, Takano S, Matsumura A, Saya H Stem Cells, 2013;31(4):627-40. Species: Mouse Sample Type: Cell Lysate
Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Authors: Steyn, F J, Lee, K, Fogarty, M J, Veldhuis, J D, McCombe, P A, Bellingham, M C, Ngo, S T, Chen, C Endocrinology, 2013;154(12):4695-706. Species: Mouse Sample Type: Plasma
SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver. Authors: Yamamoto, Masaaki, Iguchi, Genzo, Fukuoka, Hidenori, Suda, Kentaro, Bando, Hironori, Takahashi, Michiko, Nishizawa, Hitoshi, Seino, Susumu, Takahashi, Yutaka Proc Natl Acad Sci U S A, 2013;110(37):14948-53. Species: Mouse Sample Type: Serum
BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Authors: Burke R, Norman T, Haydar T, Slack B, Leeman S, Blusztajn J, Mellott T Proc Natl Acad Sci U S A, 2013;110(48):19567-72. Species: Mouse Sample Type: Tissue Homogenates
Effects of breastfeeding on body composition and maturational tempo in the rat. Authors: Crispel, Yonatan, Katz, Oren, Ben-Yosef, Dafna, Hochberg, Zeev BMC Med, 2013;11(0):114. Species: Rat Sample Type: Serum
The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function. Authors: Takehara, Yuji, Yabuuchi, Akiko, Ezoe, Kenji, Kuroda, Tomoko, Yamadera, Rie, Sano, Chiaki, Murata, Nana, Aida, Takuya, Nakama, Ken, Aono, Fumihito, Aoyama, Naoki, Kato, Keiich, Kato, Osamu Lab Invest, 2013;93(2):181-93. Species: Rat Sample Type: Cell Culture Supernates
Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. Authors: Lloyd J, Masko E, Wu C, Keenan M, Pilla D, Aronson W, Chi J, Freedland S Prostate Cancer Prostatic Dis, 2013;16(4):285-91. Species: Mouse Sample Type: Serum
Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function. Authors: Sen S, Jumaa H, Webster N Nat Commun, 2013;4(0):1336. Species: Mouse Sample Type: Serum
Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway. Authors: Ma B, Zhang Q, Wu D, Wang YL, Hu YY, Cheng YP, Yang ZD, Zheng YY, Ying HJ Acta Pharmacol. Sin., 2012;33(4):479-89. Species: Rat Sample Type: Serum
Cytosolic Malic Enzyme 1 (ME1) Mediates High Fat Diet-Induced Adiposity, Endocrine Profile, and Gastrointestinal Tract Proliferation-Associated Biomarkers in Male Mice. Authors: Al-Dwairi, Ahmed, Pabona, John Mar, Simmen, Rosalia, Simmen, Frank A PLoS ONE, 2012;7(10):e46716. Species: Mouse Sample Type: Serum
Physiological roles of group X-secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function. Authors: Sato H, Isogai Y, Masuda S J. Biol. Chem., 2011;286(13):11632-48. Species: Mouse Sample Type: Serum
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Authors: Hua Y, Sahashi K, Rigo F Nature, 2011;478(7367):123-6. Species: Mouse Sample Type: Serum
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. Authors: Maurer GD, Brucker DP, Bahr O, Harter PN, Hattingen E, Walenta S, Mueller-Klieser W, Steinbach JP, Rieger J BMC Cancer, 2011;11(0):315. Species: Mouse Sample Type: Serum
Human IGF Binding Protein-3 Overexpression Impairs Glucose Regulation in Mice via an Inhibition of Insulin Secretion. Authors: Nguyen KH, Yao XH, Moulik S, Mishra S, Nyomba BL Endocrinology, 2011;152(6):2184-96. Species: Mouse Sample Type: Plasma
Rim2alpha determines docking and priming States in insulin granule exocytosis. Authors: Yasuda T, Shibasaki T, Minami K Cell Metab., 2010;12(2):117-29. Species: Mouse Sample Type: Serum
Myocytic androgen receptor controls the strength but not the mass of limb muscles. Authors: Chambon C, Duteil D, Vignaud A, Ferry A, Messaddeq N, Malivindi R, Kato S, Chambon P, Metzger D Proc. Natl. Acad. Sci. U.S.A., 2010;107(32):14327-32. Species: Mouse Sample Type: Plasma
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Authors: Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, Savman K Neurobiol. Dis., 2010;38(1):36-46. Species: Mouse Sample Type: Tissue Homogenates
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9. Authors: Koronyo-Hamaoui M, Ko MK, Koronyo Y, Azoulay D, Seksenyan A, Kunis G, Pham M, Bakhsheshian J, Rogeri P, Black KL, Farkas DL, Schwartz M J. Neurochem., 2009;111(6):1409-24. Species: Mouse Sample Type: Tissue Homogenates
Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance. Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW Am. J. Respir. Crit. Care Med., 2008;178(2):149-57. Species: Mouse Sample Type: Serum
Reduction in hypophyseal growth hormone and prolactin expression due to deficiency in ghrelin receptor signaling is associated with Pit-1 suppression: Relevance to the immune system. Authors: Yang H, Dixit VD, Patel K, Vandanmagsar B, Collins G, Sun Y, Smith RG, Taub DD Brain Behav. Immun., 2008;0(0):. Species: Mouse Sample Type: Serum
Modulation of melanocortin signaling ameliorates uremic cachexia. Authors: Cheung WW, Rosengren S, Boyle DL, Mak RH Kidney Int., 2008;74(2):180-6. Species: Mouse Sample Type: Tissue Homogenates
Low-dose GH supplementation reduces the TLR2 and TNF-alpha expressions in visceral fat. Authors: Kubota Y, Unoki H, Bujo H, Rikihisa N, Udagawa A, Yoshimoto S, Ichinose M, Saito Y Biochem. Biophys. Res. Commun., 2008;368(1):81-7. Species: Mouse Sample Type: Plasma
Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. Authors: Paintlia AS, Paintlia MK, Singh AK, Singh I Mol. Pharmacol., 2008;73(5):1381-93. Species: Rat Sample Type: Serum
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2.Lewis rat. Authors: Yamaleyeva LM, Pendergrass KD, Pirro NT, Gallagher PE, Groban L, Chappell MC Am. J. Physiol. Heart Circ. Physiol., 2007;293(4):H2064-71. Species: Rat Sample Type: Plasma
Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Authors: Engesser-Cesar C, Anderson AJ, Cotman CW Neuroscience, 2007;144(3):1033-44. Species: Mouse Sample Type: Serum
Ghrelin promotes thymopoiesis during aging. Authors: Dixit VD, Yang H, Sun Y, Weeraratna AT, Youm YH, Smith RG, Taub DD J. Clin. Invest., 2007;117(10):2778-90. Species: Mouse Sample Type: Serum
Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models. Authors: Lanz TA, Salatto CT, Semproni AR, Marconi M, Brown TM, Richter KE, Schmidt K, Nelson FR, Schachter JB Biochem. Pharmacol., 2007;75(5):1093-103. Species: Rat Sample Type: Plasma
GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. Authors: Wanderling S, Simen BB, Ostrovsky O, Ahmed NT, Vogen SM, Gidalevitz T, Argon Y Mol. Biol. Cell, 2007;18(10):3764-75. Species: Mouse Sample Type: Cell Culture Supernates
Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation. Authors: Wang J, Wang C, Tsui HW, Las Heras F, Cheng EY, Iscove NN, Chiu B, Inman RD, Pritzker KP, Tsui FW Exp. Cell Res., 2007;313(20):4120-9. Species: Mouse Sample Type: Serum
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